Species: Hu, Rt
Applications: WB, Flow, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB, IHC, ICC/IF
Host: Mouse Monoclonal
Species: Hu, Rt
Applications: Flow, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
Calponin is a smooth muscle specific, actin-, tropomyosin- and calmodulin-binding protein thought to be involved in regulation of actomyosin as well as the regulation or modulation of contraction (1). Calponin binds filamentous actin (F-actin) through two distinct sites ABS1 and ABS2, with an affinity in the low micromolar range (2) Immunoreactivity for calponin, along with alpha-smooth muscle actin and smooth muscle myosin heavy chains, confirms the known neoplastic myoepithelial component of adenoid cystic carcinomas and epithelial-myoepithelial carcinomas. The consistently positive staining pattern in adenoid cystic carcinomas may be diagnostically useful in discriminating histologically similar but consistently negative polymorphous low-grade adenocarcinomas (3).
Bioinformatics
| Entrez |
Human
Mouse
Rat
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
1264 |
| Alternate Names |
- Basic calponin
- calponin 1, basic, smooth muscle
- Calponin H1, smooth muscle
- calponins, basic
- Sm-Calp
- SMCCcalponin-1
|
Research Areas for Calponin 1
Find related products by research area and learn more about each of the different research areas below.
CancerCytoskeleton Markers
