Cadherin-19 Products

Description

CDH19 is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.

Bioinformatics

Entrez	28513 Human
Uniprot	NP_066976 Human NP_066976.1 Human Q9H159 Human
Product By Gene ID	28513
Alternate Names	cadherin 19, type 2 cadherin-19 CDH7CDH7L2