BAF57 Products

Description

BAF57 is encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.

Bioinformatics

Entrez	57376 Mouse 6605 Human
Uniprot	AAH07082.1 Human NM_003079 Human NP_003070 Human NP_003070. Human NP_003070.3 Human Q969G3 Human
Product By Gene ID	6605
Alternate Names	BAF57BRG1-associated factor 57 chromatin remodeling complex BRG1-associated factor 57 subfamily e, member 1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin SWI/SNF-related matrix-associated actin-dependent regulator of chromatin e1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily E member 1

Research Areas for BAF57

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
DNA Repair
DNA replication, Transcription, Translation and Splicing