ARHGEF11 Products

Description

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq]

Bioinformatics

Entrez	9826 Human
Uniprot	AAH57394 Human NP_055599.1 Human O15085 Human
Product By Gene ID	9826
Alternate Names	DKFZp667F1223 glutamate transporter EAAT4-associated protein 48 GTRAP48 KIAA0380rho guanine nucleotide exchange factor 11 PDZ-RhoGEF PDZ-RHOGEF Rho guanine exchange factor (GEF) 11 Rho guanine nucleotide exchange factor (GEF) 11 RhoA-specific guanine nucleotide exchange factor RhoGEF glutamate transport modulator