ARHGAP22 Products

Description

ARHGAP22 is a Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. It acts as a GTPase activator for RAC1 by converting it to an inactive GDP-bound state and also inhibits RAC1-dependent lamellipodia formation. It may also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter.

Bioinformatics

Entrez	58504 Human
Uniprot	Q7Z5H3 Human
Product By Gene ID	58504
Alternate Names	Rho GTPase activating protein 22 rho GTPase-activating protein 22 RhoGAP2 RHOGAP2 Rho-type GTPase-activating protein 22

Research Areas for ARHGAP22

Find related products by research area and learn more about each of the different research areas below.

Diabetes Research
Lipid and Metabolism
Phospho-Specific