Species: Hu
Applications: WB, IHC, ICC/IF
Host: Sheep Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
AF6/Afadin was identified as part of a fusion with MLL (mixed lineage leukemia) in a t(6;11) genetic translocation. AF6/Afadin is also known as afadin (a splicing variant of AF6/Afadin found at adherins junction). AF6/afadin is an actin filament binding protein that binds to nectin at cadherin-based cell-cell adherens junctions and regulates cell-cell adhesion by mediating Ras signaling.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
4301 |
| Alternate Names |
- AF64
- afadin
- FLJ34371
- myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila);translocated to, 4
|
![Western Blot Afadin/AF-6 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Afadin_AF7829_Western_Blot_12834.jpg)
![Immunocytochemistry Afadin/AF-6 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Afadin_AF7829_Immunocytochemistry_14433.jpg)
![Immunohistochemistry Afadin/AF-6 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Afadin_AF7829_Immunohistochemistry_12854.jpg)
![Western Blot Afadin/AF-6 Antibody (851204) [Unconjugated]](http://images.novusbio.com/fullsize2/Afadin_MAB78291_Western_Blot_16495.jpg)
![Immunocytochemistry Afadin/AF-6 Antibody (851204) [Unconjugated]](http://images.novusbio.com/fullsize2/Afadin_MAB78291_Immunocytochemistry_16482.jpg)
