Actin Gamma 1 Products

Description

Actin, gamma 1 (ACTG1) is a member of the actin protein family, a highly conserved protein group with three main isoforms: alpha, beta and gamma. Alpha actins are mainly expressed in muscle tissues where they are a major constituent of the contractile apparatus, whereas beta and gamma actin proteins are widely expressed in most cell types where they are predominantly involved in cell motility and cytoskeleton maintenance. Actin gamma 1 is a cytoplasmic actin isoform usually found in nonmuscle cells.

Actin Gamma 1 antibodies serve as excellent loading controls, due to the proteins' near ubiquitous expressn and strong conservation across most species. In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cyto-skeleton and as mediators of internal cell motility. Beta actins are highly conserved proteins that are involved in cell motility, structure and integrity. Beta actins are cytoplasmic proteins ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Actin Gamma 1 antibody serves as an excellent loading control.

Bioinformatics

Entrez	11465 Mouse 287876 Rat 71 Human
Uniprot	AAH53572 Human NP_001605 Human P63261 Human
Product By Gene ID	71
Alternate Names	ACT ACTB ACTG actin, cytoplasmic 2 actin, gamma 1 cytoskeletal gamma-actin deafness, autosomal dominant 20; deafness, autosomal dominant 26 DFNA20 DFNA26 Gamma-actin

Research Areas for Actin Gamma 1

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Cellular Markers
Cytoskeleton Markers
Loading Controls
Stem Cell Markers