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Nse2 Antibody

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Western Blot: Nse2 Antibody [H00286053-B01P] - Analysis of NSMCE2 expression in transfected 293T cell line by NSMCE2 polyclonal antibody. Lane 1: C8orf36 transfected lysate(27.17 KDa). Lane 2: Non-transfected lysate.
Western Blot: Nse2 Antibody [H00286053-B01P] - Analysis of NSMCE2 expression in transfected 293T cell line by NSMCE2 polyclonal antibody. Lane 1: C8orf36 transfected lysate(27.17 KDa). Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: Nse2 Antibody [H00286053-B01P] - Analysis of purified antibody to NSMCE2 on HeLa cell. (antibody concentration 10 ug/ml)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Mouse
Conjugate
Unconjugated

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Nse2 Antibody Summary

Immunogen
C8orf36 (NP_775956, 1 a.a. - 247 a.a.) full-length human protein. MPGRSSSNSGSTGFISFSGVESALSSLKNFQACINSGMDTASSVALDLVESQTEVSSEYSMDKAMVEFATLDRQLNHYVKAVQSTINHVKEERPEKIPDLKLLVEKKFLALQSKNSDADFQNNEKFVQFKQQLKELKKQCGLQADREADGTEGVDEDIIVTQSQTNFTCPITKEEMKKPVKNKVCGHTYEEDAIVRMIESRQKRKKKAYCPQIGCSHTDIRKSDLIQDEALRRAIENHNKKRHRHSE
Isotype
IgG
Clonality
Polyclonal
Host
Mouse
Gene
NSMCE2
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
This antibody is useful for Western Blot, Immunofluorescence

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Nse2 Antibody

  • C8orf36
  • E3 SUMO-protein ligase NSE2
  • EC 6.3.2
  • EC 6.3.2.-
  • FLJ32440
  • hMMS21
  • methyl methanesulfonate sensitivity gene 21
  • MMS21 homolog
  • MMS21chromosome 8 open reading frame 36
  • non-SMC element 2 homolog (MMS21, S. cerevisiae)
  • Non-SMC element 2 homolog
  • non-SMC element 2, MMS21 homolog (S. cerevisiae)
  • Non-structural maintenance of chromosomes element 2 homolog
  • NSE2

Background

E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks byhomologous recombination. The complex may promote sister chromatid homologous recombination by recruiting theSMC1-SMC3 cohesin complex to double-strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteinssuch as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is requiredfor the prevention of DNA damage-induced apoptosis by facilitating DNA repair

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NSMCE2
Uniprot