Human SLC6A4/5-HTTLPR/Serotonin transporter ELISA Kit (Colorimetric) Summary
Specificity |
This kit recognizes Human SERT in samples. No significant cross-reactivity or interference between Human SERT and analogues was observed. |
Standard Curve Range |
15.63 - 1000 pg/mL |
Sensitivity |
9.38 pg/mL |
Assay Type |
Sandwich-ELISA |
Inter-Assay |
CV% < 5.35% |
Intra-Assay |
CV% < 4.63% |
Spike Recovery |
86-103% |
Sample Volume |
100 uL |
Kit Type |
ELISA Kit (Colorimetric) |
Gene |
SLC6A4 |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Storage of components varies. See protocol for specific instructions. |
Kit Components
Components
|
- Biotinylated Detection Ab Diluent
- Concentrated Biotinylated Detection Ab (100x)
- Concentrated HRP Conjugate (100x)
- Concentrated Wash Buffer (25x)
- HRP Conjugate Diluent
- Micro ELISA Plate (Dismountable)
- Plate Sealer
- Product Manual
- Reference Standard
- Sample Diluent
- Stop Solution
- Substrate Reagent
|
Alternate Names for Human SLC6A4/5-HTTLPR/Serotonin transporter ELISA Kit (Colorimetric)
Background
Serotonin transporter encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are
guaranteed for 6 months from date of receipt.
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