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SMC6L1 Antibody

Images

 
Immunohistochemistry-Paraffin: SMC6L1 Antibody [NBP2-33378] - Staining of human testis shows weak nuclear positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: SMC6L1 Antibody [NBP2-33378] - Staining of human placenta shows weak nuclear positivity in a subset of trophoblastic cells.
Immunohistochemistry-Paraffin: SMC6L1 Antibody [NBP2-33378] - Staining of human prostate shows weak nuclear positivity in glandular cells.
Immunohistochemistry-Paraffin: SMC6L1 Antibody [NBP2-33378] - Staining of human skeletal muscle shows no nuclear positivity in striated muscle fibers as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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SMC6L1 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: KEEHGKIKREELDVKHALSYNQRQLKELKDSKTDRLKRFGPNVPALLEAIDDAYRQGHFTYKPVGPLGACIHLRDPELALAIESCL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SMC6
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
SMC6L1 Protein (NBP2-33378PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (81%), Rat (84%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for SMC6L1 Antibody

  • FLJ22116
  • hSMC6
  • SMC protein 6
  • SMC6 structural maintenance of chromosomes 6-like 1 (yeast)
  • SMC6 structural maintenance of chromosomes 6-like 1
  • SMC-6
  • SMC6L1FLJ35534
  • structural maintenance of chromosomes 6
  • structural maintenance of chromosomes protein 6

Background

SMC (Structural maintenance of chromosomes) proteins are members of multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. Two of these complexes, cohesin and condensin consist of a core complex of an SMC1 and SMC3 heterodimer or an SMC2 and SMC4 heterodimer, respectively. A third complex includes a heterodimer of SMC5 and SMC6 whose function is not fully understood but is proposed to be related to DNA repair.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SMC6
Uniprot