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SCN1B Antibody

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Western Blot: SCN1B Antibody [NBP3-10371] - Western blot analysis of SCN1B in Rat Thymus as a positive control. Antibody dilution at 1.0 ug/ml

Product Details

Summary
Reactivity RtSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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SCN1B Antibody Summary

Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Rat SCN1B (NP_058984). Peptide sequence TFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIF
Clonality
Polyclonal
Host
Rabbit
Gene
SCN1B
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1.0 ug/ml
Theoretical MW
23 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for SCN1B Antibody

  • GEFSP1
  • sodium channel beta-1 subunit
  • sodium channel subunit beta-1
  • sodium channel, voltage-gated, type I, beta polypeptide
  • sodium channel, voltage-gated, type I, beta

Background

Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional SCN1B Products

Array NBP3-10371

Research Areas for SCN1B Antibody (NBP3-10371)

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Bioinformatics

Gene Symbol SCN1B