I am looking for a "Primary antibody for GABAa receptor gamma 2" raised from antigen whose aa sequence is between exon 5-10. The application will be for "Immunohistochemistry". I would like to know if you have a product to match it?

Name: GABA-A R gamma 2 Antibody
Brand: Novus Biologicals
SKU: NB300-190
Price: 399 USD

Question

Accepted Answer

NB300-190 is direceted against GABA A receptor gamma 2, is suitable for use in IHC and uses a fusion protein from the cytoplasmic loop of the gamma 2 subunit as an antigen, so this should suit your needs.

At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	Hu, Mu, Rt, Bv, Ca, Ch, PmSpecies Glossary
Applications	WB, IHC, KD
Clonality	Polyclonal
Host	Rabbit
Conjugate	Unconjugated

Immunogen	Fusion protein from the cytoplasmic loop of the gamma 2 subunit. Accession # P18508
Specificity	Specific for endogenous levels of the ~46 kDa gamma 2-subunit of the GABAA receptor.
Predicted Species	Bovine (100%), Chicken (100%), Canine (100%), Primate (100%). Backed by our 100% Guarantee.
Isotype	IgG
Clonality	Polyclonal
Host	Rabbit
Gene	GABRG2
Purity	Antigen Affinity-purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Store at -20C. Avoid freeze-thaw cycles.
Buffer	10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
Preservative	No Preservative
Purity	Antigen Affinity-purified

Publications using NB300-190	Applications	Species
Chan ES, Ge Y, So YW et al. Allosteric potentiation of GABAA receptor single-channel conductance by netrin-1 during neuronal-excitation-induced inhibitory synaptic homeostasis Cell reports 2022-11-01 [PMID: 36323250] (WB, Mouse)	WB	Mouse
Janach G, BOhm M, DOhne N et al. Interferon-gamma enhances neocortical synaptic inhibition by promoting membrane association and phosphorylation of GABAA receptors in a protein kinase C-dependent manner Brain, Behavior, and Immunity 2022-01-01 [PMID: 34998939] (WB, Rat)	WB	Rat
He Y, Cai X, Liu H Et Al. 5-HT recruits distinct neurocircuits to inhibit hunger-driven and non-hunger-driven feeding Molecular psychiatry 2021-07-21 [PMID: 34290371]
Kim ER, Xu Y, Cassidy RM et al. Paraventricular hypothalamus mediates diurnal rhythm of metabolism Nat Commun 2020-07-30 [PMID: 32732906] (IF/IHC, Mouse)	IF/IHC	Mouse
Shimell JJ, Shah BS, Cain SM et al. The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse Formation Cell Rep 2019-11-19 [PMID: 31747610] (KD, Human, Mouse, Rat)	KD	Human, Mouse, Rat
Fan J, Li D, Chen HS et al. Metformin Produces Anxiolytic-like Effects in Rats by Facilitating GABAA Receptor Trafficking to Membrane. Br. J. Pharmacol. 2018-10-14 [PMID: 30318707] (WB, Rat)	WB	Rat
Huang S, Hokenson K, Bandyopadhyay S et al. Brief Dark Exposure Reduces Tonic Inhibition in Visual Cortex. J. Neurosci. 2015-12-02 [PMID: 26631472] (WB, Mouse)	WB	Mouse
Johnson AC, Nagle KJ, Tremble SM, Cipolla MJ. The Contribution of Normal Pregnancy to Eclampsia. PLoS ONE. 2015-07-29 [PMID: 26218425] (WB, Rat)	WB	Rat
Wu Z, Kim ER, Sun H et al. GABAergic projections from lateral hypothalamus to paraventricular hypothalamic nucleus promote feeding J. Neurosci. 2015-02-25 [PMID: 25716832] (IF/IHC, Mouse)	IF/IHC	Mouse
Fatemi SH, Reutiman TJ, Folsom TD et al. Downregulation of GABAA Receptor Protein Subunits alpha6, beta2, delta, epsilon, gamma2, theta, and p2 in Superior Frontal Cortex of Subjects with Autism. J Autism Dev Disord 2014-03-26 [PMID: 24668190] (WB, Human)	WB	Human
Carlson SL, O'Buckley TK, Thomas R et al. Altered GABAA Receptor Expression and Seizure Threshold Following Acute Ethanol Challenge in Mice Lacking the RIIbeta Subunit of PKA. Neurochem Res. 2013-10-09 [PMID: 24104609] (WB, Mouse)	WB	Mouse
Bleckert A, Parker ED, Kang Y, et al. Spatial Relationships between GABAergic and Glutamatergic Synapses on the Dendrites of Distinct Types of Mouse Retinal Ganglion Cells across Development. PLoS One 2013-07-26 [PMID: 23922756] (WB, Mouse)	WB	Mouse
Joshi S, Sun C, Kapur J. A mouse monoclonal antibody against the gamma2 subunit of GABAA receptors. Hybridoma (Larchmt) 2011-12-01 [PMID: 22149279]
Dalby N, Leurs U, Falk-Petersen C et al. Kinase activity simultaneously determines the constitutive and the orthosteric gating in alpha4beta1/3delta GABAA receptors in hippocampal granule cells bioRxiv 2018-05-09
Kharlamov EA, Lepsveridze E, Meparishvili M et al. Alterations of GABA(A) and glutamate receptor subunits and heat shock protein in rat hippocampus following traumatic brain injury and in posttraumatic epilepsy. Epilepsy Res;95(1-2):20-34. 2011-06-01 [PMID: 21439793] (WB, Rat)	WB	Rat
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GABA-A R gamma 2 Antibody

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Gene Symbol	GABRG2
Entrez	2566(Human) 14406(Mouse) 29709(Rat)
Uniprot	P18508(Rat)