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KLRG1 Antibody (2388C) [Unconjugated]

 (2 Publications)
 (1 Review)
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Human peripheral blood was stained with (A) Rabbit anti-Human KLRG1 Monoclonal Antibody (Catalog # MAB70293) or (B) Rabbit IgG control antibody (Catalog # MAB1050) followed by APC-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog # F0111) and CD56 PE-conjugated Monoclonal Antibody (Catalog # FAB2408P). View our protocol for Staining Membrane-associated Proteins.
Human peripheral blood was stained with (A) Rabbit anti-Human KLRG1 Monoclonal Antibody (Catalog # MAB70293) or (B) Rabbit IgG control antibody (Catalog # MAB1050) followed by APC-conjugated Anti-Rabbit IgG Secondary ...read more
KLRG1 was detected in immersion fixed paraffin-embedded sections of human tonsil using Rabbit Anti-Human KLRG1 Monoclonal Antibody (Catalog # MAB70293) at 3 µg/mL for 1 hour at room temperature followed by ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, CyTOF-ready
Clone
2388C
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB70293U-100UG
Alexa Fluor 405
FAB70293V-100UG
Alexa Fluor 488
FAB70293G-100UG
Alexa Fluor 532
FAB70293X
Alexa Fluor 594
FAB70293T-100UG
Alexa Fluor 647
FAB70293R-100UG
Alexa Fluor 700
FAB70293N-100UG
Alexa Fluor 750
FAB70293S-100UG
Allophycocyanin
FAB70293A
Allophycocyanin/Cy7
FAB70293APCCY7
Biotin
FAB70293B
CoraFluor 1
FAB70293CL1
DyLight 350
FAB70293D
DyLight 405
FAB70293E
DyLight 488
FAB70293K
DyLight 550
FAB70293L
DyLight 594
FAB70293M
DyLight 650
FAB70293W
DyLight 680
FAB70293Y
DyLight 755
FAB70293Z
FITC
FAB70293F
HRP
FAB70293H
Janelia Fluor 525
FAB70293JF525
Janelia Fluor 549
FAB70293I
Janelia Fluor 585
FAB70293JF585
Janelia Fluor 635
FAB70293JF635
Janelia Fluor 646
FAB70293J
Janelia Fluor 669
FAB70293JF669
PE
FAB70293P
PE/Atto594
FAB70293PEATT594
PE/Cy5.5
FAB70293PECY55
PE/Cy7
FAB70293PECY7
PerCP
FAB70293C
mFluor Violet 450 SE
FAB70293MFV450
mFluor Violet 500 SE
FAB70293MFV500
mFluor Violet 610 SE
FAB70293MFV610
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB70293-SP
Carrier Free
FAB70293V-100UG
Carrier Free
FAB70293U-100UG
Carrier Free
FAB70293T-100UG
Carrier Free
FAB70293S-100UG
Carrier Free
FAB70293R-100UG
Carrier Free
FAB70293N-100UG
Carrier Free
FAB70293G-100UG
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KLRG1 Antibody (2388C) [Unconjugated] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
 Chinese hamster ovary cell line CHO-derived recombinant  human KLRG1
Leu60-Phe195
Accession # Q96E93
Specificity
Detects human KLRG1 in direct ELISAs.
Source
N/A
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Purity Statement
Protein A or G purified from cell culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 0.25 ug/10^6 cells
  • Immunohistochemistry 3-25 ug/mL
Reviewed Applications
Read 1 Review rated 4
using
MAB70293 in the following applications:
Publications
Read Publications using
MAB70293 in the following applications:

  • IHC
    2 publications

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for KLRG1 Antibody (2388C) [Unconjugated]

  • 2F1
  • CLEC15A
  • CLEC15AMAFA-LIKE
  • C-type lectin domain family 15 member A
  • C-type lectin domain family 15, member A
  • ITIM-containing receptor MAFA-L
  • killer cell lectin-like receptor subfamily G member 1
  • killer cell lectin-like receptor subfamily G, member 1
  • KLRG1
  • MAFA
  • MAFAL
  • MAFA-L
  • MAFA-like receptor
  • MAFAMAFA-2F1
  • mast cell function-associated antigen (ITIM-containing)
  • Mast cell function-associated antigen
  • MGC13600

Background

KLRG1 (killer cell lectin-like receptor G1), also called MAFA (mast cell function associated), is a 30-38 kDa type II transmembrane inhibitory glycoprotein of the C‑type lectin family, designated CLEC15A. KLRG1 cDNA encodes 195 amino acids (aa) including an intracellular ITIM motif and a 136 aa extracellular domain (ECD) with a single C‑type lectin domain. The human KLRG1 ECD shares 57% and 54% aa identity with mouse and rat KLRG1, respectively. A 189 aa isoform diverges at aa 186. KLRG1 binds E-, N- and R-cadherins and functions as an MHC‑independent means of identifying non-self pathogens and epithelial tumor cells with low E‑cadherin expression. It is expressed as a monomer or disulfide‑linked homodimer on NK and T cell subsets such as tumor-infiltrating lymphocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for KLRG1 Antibody (MAB70293)(2)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC.


Filter By Application
IHC
(2)
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Filter By Species
Human
(2)
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Review for KLRG1 Antibody (MAB70293) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using MAB70293:
Filter by Applications
IHC-Fr
(1)
All Applications
Filter by Species
Human
(1)
All Species
Images Ratings Applications Species Date Details
Immunohistochemistry-Frozen KLRG1 MAB70293
Enlarge 		4
reviewed by:
Verified Customer
 IHC-Fr Human 03/30/2020
View

Summary

ApplicationImmunohistochemistry-Frozen
Sample TestedTonsil
SpeciesHuman
LotN/A

Product General Protocols

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FAQs for KLRG1 Antibody (MAB70293) (0)

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Secondary Antibodies

 

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Immunohistochemistry-Frozen KLRG1 MAB70293
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 Verified Customer
03/30/2020
Application: IHC-Fr
Species: Human
read this review

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