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Dopamine D3R/DRD3 Antibody

Images

 
Western Blot: Dopamine D3R/DRD3 Antibody [NBP3-12391] - 1:750 antibody dilution in DiluOBuffer. Predicted bad size 50 KDa. Observed band size 50 KDa.
Immunocytochemistry/ Immunofluorescence: Dopamine D3R/DRD3 Antibody [NBP3-12391] - PC12 cells. Cells were incubated with primary antibody 5 ug/ml overnight at 4c.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, DB, ELISA, ICC/IF, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Dopamine D3R/DRD3 Antibody Summary

Immunogen
Synthetic peptide corresponding to unique amino acid sequence on Dopamine Receptor D3 protein, peptide was covalently modified. Sequence: CQACHVSPELYRATTWGY
Clonality
Polyclonal
Host
Rabbit
Gene
DRD3
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Dot Blot 1:50000
  • ELISA 1:50000
  • Immunocytochemistry/ Immunofluorescence 5 ug/ul
  • Immunoprecipitation
  • Western Blot 1:1000-1:15000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Dopamine D3R/DRD3 Antibody

  • D(3) dopamine receptor
  • D3DR
  • Dopamine D3 R
  • Dopamine D3 receptor
  • Dopamine D3R
  • dopamine receptor D3
  • DRD3
  • essential tremor 1
  • ETM1
  • FET1
  • MGC149204
  • MGC149205

Background

The DRD3 Dopamine Receptor is expressed in brain regions associated with cognitive, emotional, and endocrine functions. DRD3 mediates the effects of drugs used in the treatment of schizophrenia and Parkinson's disease. DRD3 also binds BP897, a potent inhibitor of drug-craving and cocaine-seeking behaviors. Mutations in DRD3 lead to sodium retention in the kidney, resulting in hypertension and increased locomotor activity in mice. Multiple isoforms of DRD3 are produced by alternative splicing.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DRD3