Name: Islet-1 Antibody [Unconjugated]
Brand: Novus Biologicals
SKU: AF1837
Price: 489 USD

- COVID-19 Research Tools
  
  Antibodies
  Primary Antibodies
  Conjugated Antibodies
  
  Sample Size Antibodies
  
  KO Validated Antibodies
  
  Recombinant Antibodies
  
  Antibody Sampler Packs
  
  Antibody Pairs
  
  Secondary Antibodies
  
  Isotype Control Antibodies
  
  Proteins and Peptides
  Peptides & Proteins
  
  Blocking Peptides
  
  Biologically Active Proteins
  
  Lysates and Cell Lines
  Lysates
  
  Stem Cell Lines
- Kits
  Antibody Labeling Kits
  
  ChIP Kits
  
  ELISA Kits
  
  Flow Cytometry Kits
  
  Activators and Inhibitors
  Inhibitors
  
  Activators
  
  Support Products
  Exosome Isolation
  
  Flow Cytometry Beads
  
  IHC Tissue Slides
  
  IHC Microarrays
  
  Western Blot Gels & Buffers
  
  Western Blot Membranes
  
  All Support Products
  
  Bulk and Custom
Products
Our Protocols
- Resources
  Protocols
  
  Video Protocols
  
  Troubleshooting Guides
  
  Posters and Literature
  
  Handbooks and Guides
  
  Calculators
  
  FAQs
  
  Blogs
  
  Diseases
  
  Whitepapers
  
  Antibody Concierge
  
  Webinars
- Tools
  Spectra Viewer
  
  Flow Cytometry Panel Builder
  
  Application
  ELISA
  
  Flow Cytometry
  
  Mass Cytometry (CyTOF)
  
  ICC
  
  IHC
  
  Western Blotting
  
  Interviews
  Faculty
  
  Postdoc
Resources
View Pathways
- By Research Area
  Apoptosis
  
  Autophagy
  
  Cancer
  
  Cell Biology
  
  Cellular Markers
  
  Epigenetics
  
  Epitope Tags
  
  Exosomes Research
  
  Hypoxia
  
  Immunology
  
  Microbiology
  
  Neuroscience
  
  Stem Cells
- By Pathway
  AKT
  
  Apoptosis
  
  Autophagy
  
  ERK1/2/5 Pathway
  
  Hedgehog
  
  Hippo
  
  JNK Pathway
  
  mTOR
  
  Necroptosis
  
  NFKB Signaling
  
  p38 Signaling
  
  TGF Beta
  
  TLR
Research Areas
Get Rewards
- Customer Care
  100% Guarantee
  
  Risk Free Testing
  
  Novus Rewards Program
  
  Publication Rewards Program
  
  New Lab Discount
  
  Scholarship
  
  Travel Grants
  
  Promotions
Customer Care
Novus Careers
- About us
  Careers
  
  Collaborations
  
  Events
  
  Novus Story
  
  Our Team
  
  Philanthropy
  
  Press Releases
  
  Why choose Novus
About Us
- Contact Us
  Customer Service
  
  Distributors
  
  Technical Support
Contact

At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	WB, Simple Western, IHC, ICC/IF
Clonality	Polyclonal
Host	Goat
Conjugate	Unconjugated
Concentration	LYOPH

Catalog# & Conjugate	Size	Price
Biotin BAF1837

NL557 NL1837R

Catalog# & Formulation	Size	Price
Carrier Free NL1837R

Carrier Free AF1837-SP

Conjugate	Catalog #	Availability	Size	Price
Biotin	BAF1837
NL557	NL1837R

Islet-1 Antibody [Unconjugated]

Species Glossary

Images

Product Details

Order Details

Islet-1 Antibody [Unconjugated] Summary

Applications/Dilutions

Packaging, Storage & Formulations

Notes

Alternate Names for Islet-1 Antibody [Unconjugated]

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for Islet-1 Antibody (AF1837)(36)

Reviews for Islet-1 Antibody (AF1837) (0)

Product General Protocols

Video Protocols

FAQs for Islet-1 Antibody (AF1837) (0)

Secondary Antibodies

Isotype Controls

Additional Islet-1 Products

Blogs on Islet-1

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Review this Product

Bioinformatics

Immunogen	E. coli-derived recombinant human Islet-1 Met4-Ala349 Accession # P61371
Specificity	Detects human Islet-1 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant human Islet-2 is observed.
Source	N/A
Isotype	IgG
Clonality	Polyclonal
Host	Goat
Gene	ISL1
Purity Statement	Antigen Affinity-purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Reconstitution Instructions	Reconstitute at 0.2 mg/mL in sterile PBS.

Publications using AF1837	Applications	Species
Briana N. Ondatje, Samuel Sances, Michael J. Workman, Clive N. Svendsen Tissue clearing of human iPSC-derived organ-chips enables high resolution imaging and analysis† Lab on a Chip 10/25/2022 [PMID: 36205191]
Kazuaki Maruyama, Sachiko Miyagawa-Tomita, Yuka Haneda, Mayuko Kida, Fumio Matsuzaki, Kyoko Imanaka-Yoshida et al. The cardiopharyngeal mesoderm contributes to lymphatic vessel development in mouse eLife 10/5/2022 [PMID: 36196867]
Nicholas E. Albrecht, Danye Jiang, Viktor Akhanov, Robert Hobson, Colenso M. Speer, Michael A. Robichaux et al. Rapid 3D-STORM imaging of diverse molecular targets in tissue Cell Reports Methods 7/18/2022 [PMID: 35880013]
Camille Januel, Giovanna Menduti, Kamel Mamchaoui, Cecile Martinat, Ruben Artero, Piotr Konieczny et al. Moxifloxacin rescues SMA phenotypes in patient-derived cells and animal model Cellular and Molecular Life Sciences 8/1/2022 [PMID: 35864358]
S Gupta, R Kawaguchi, E Heinrichs, S Gallardo, S Castellano, I Mandric, BG Novitch, SJ Butler Inï¿½vitro atlas of dorsal spinal interneurons reveals Wnt signaling as a critical regulator of progenitor expansion Oncogene, 2022-07-19;40(3):111119. 2022-07-19 [PMID: 35858555] (IHC, Human)	IHC	Human
M Ohgushi, N Taniyama, A Vandenbon, M Eiraku Delamination of trophoblast-like syncytia from the amniotic ectodermal analogue in human primed embryonic stem cell-based differentiation model Cell Reports, 2022-06-21;39(12):110973. 2022-06-21 [PMID: 35732132] (Flow Cytometry, ICC, Human)	Flow Cytometry, ICC	Human
Barbara Gonzalez-Teran, Maureen Pittman, Franco Felix, Reuben Thomas, Desmond Richmond-Buccola, Ruth Hüttenhain et al. Transcription factor protein interactomes reveal genetic determinants in heart disease Cell 3/1/2022 [PMID: 35182466]
X Zhou, Y Lu, F Zhao, J Dong, W Ma, S Zhong, M Wang, B Wang, Y Zhao, Y Shi, Q Ma, T Lu, J Zhang, X Wang, Q Wu Deciphering the spatial-temporal transcriptional landscape of human hypothalamus development Cell Stem Cell, 2021-12-07;0(0):. 2021-12-07 [PMID: 34879244] (IHC, Human)	IHC	Human
Jessica G. Cunningham, James D. Scripter, Stephany A. Nti, Eric S. Tucker Early construction of the thalamocortical axon pathway requires c‐Jun N‐terminal kinase signaling within the ventral forebrain Developmental Dynamics 3/1/2022 [PMID: 34494344]
Mary Jo Talley, Diana Nardini, Shenyue Qin, Carlos E. Prada, Lisa A. Ehrman, Ronald R. Waclaw A role for sustained MAPK activity in the mouse ventral telencephalon Developmental Biology 8/1/2021 [PMID: 33775695]
Sandeep Gupta, Ken Yamauchi, Bennett G. Novitch, Samantha J. Butler Derivation of dorsal spinal sensory interneurons from human pluripotent stem cells STAR Protocols 3/4/2021 [PMID: 33659900]
Katherine Exelby, Edgar Herrera-Delgado, Lorena Garcia Perez, Ruben Perez-Carrasco, Andreas Sagner, Vicki Metzis et al. Precision of tissue patterning is controlled by dynamical properties of gene regulatory networks Development 2/15/2021 [PMID: 33547135]
Ewan EE, Carlin D, Goncalves TM et al. Ascending dorsal column sensory neurons respond to spinal cord injury and downregulate genes related to lipid metabolism Sci Rep 1/12/2021 [PMID: 33431991]
Ho R, Workman MJ, Mathkar P et al. Cross-Comparison of Human iPSC Motor Neuron Models of Familial and Sporadic ALS Reveals Early and Convergent Transcriptomic Disease Signatures Cell systems 12/23/2020 [PMID: 33382996]
L Zhang, J Avery, A Yin, AM Singh, TS Cliff, H Yin, S Dalton Generation of Functional Brown Adipocytes from Human Pluripotent Stem Cells via Progression through a Paraxial Mesoderm State Cell Stem Cell, 2020-08-11;0(0):. 2020-08-11 [PMID: 32783886] (IHC, Human)	IHC	Human
Coyne AN, Zaepfel BL, Hayes L et al. G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD Neuron 7/8/2020 [PMID: 32673563]
Eugene Kim, Ming Jiang, Huachao Huang, Yongchun Zhang, Natalie Tjota, Xia Gao et al. Isl1 Regulation of Nkx2.1 in the Early Foregut Epithelium Is Required for Trachea-Esophageal Separation and Lung Lobation Developmental Cell 12/1/2019 [PMID: 31813798]
Jiang D, Burger CA, Casasent AK et al. Spatiotemporal gene expression patterns reveal molecular relatedness between retinal laminae J. Comp. Neurol. 10/14/2019 [PMID: 31609468]
ME Frendo, A da Silva, KD Phan, S Riche, SJ Butler The cofilin/Limk1 pathway controls the growth rate of both developing and regenerating motor axons J. Neurosci., 2019-10-02;0(0):. 2019-10-02 [PMID: 31578231] (IHC, Mouse)	IHC	Mouse
Lauren Drowley, Jane McPheat, Anneli Nordqvist, Samantha Peel, Ulla Karlsson, Sofia Martinsson et al. Discovery of retinoic acid receptor agonists as proliferators of cardiac progenitor cells through a phenotypic screening approach Stem Cells Translational Medicine 1/1/2020 [PMID: 31508905]
Carlin D, Halevi AE, Ewan EE et al. Nociceptor Deletion of Tsc2 Enhances Axon Regeneration by Inducing a Conditioning Injury Response in Dorsal Root Ganglia eNeuro 6/25/2019 [PMID: 31182472]
T Colunga, M Hayworth, S Kre beta , DM Reynolds, L Chen, KL Nazor, J Baur, AM Singh, JF Loring, M Metzger, S Dalton Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair Cell Rep, 2019-03-05;26(10):2566-2579.e10. 3/5/2019 [PMID: 30840882]
Peng YR, Tran NM, Krishnaswamy A et al. Satb1 Regulates Contactin 5 to Pattern Dendrites of a Mammalian Retinal Ganglion Cell Neuron 8/16/2017 [PMID: 28781169]
Paloma Merchan-Sala, Diana Nardini, Ronald R. Waclaw, Kenneth Campbell Selective neuronal expression of the SoxE factor, Sox8, in direct pathway striatal projection neurons of the developing mouse brain Journal of Comparative Neurology 9/1/2017 [PMID: 28472858]
RR Waclaw, LA Ehrman, P Merchan-Sa, V Kohli, D Nardini, K Campbell Foxo1 is a downstream effector of Isl1 in direct pathway striatal projection neuron development within the embryonic mouse telencephalon Mol. Cell. Neurosci, 2017-02-14;80(0):44-51. 2017-02-14 [PMID: 28213137] (IHC, Mouse)	IHC	Mouse
CJ Woo, VK Maier, R Davey, J Brennan, G Li, J Brothers, B Schwartz, S Gordo, A Kasper, TR Okamoto, HE Johansson, B Mandefro, D Sareen, P Bialek, BN Chau, B Bhat, D Bullough, J Barsoum Gene activation of SMN by selective disruption of lncRNA-mediated recruitment of PRC2 for the treatment of spinal muscular atrophy Proc. Natl. Acad. Sci. U.S.A, 2017-02-13;114(8):E1509-E1518. 2017-02-13 [PMID: 28193854] (ICC, Human)	ICC	Human
Cell freezing protocol suitable for ATAC-Seq on motor neurons derived from human induced pluripotent stem cells Sci Rep, 2016-05-05;6(0):25474. 2016-05-05 [PMID: 27146274] (IHC-P, Human)	IHC-P	Human
Adams , Katrina, Rousso , David L, Umbach , Joy A, Novitch , Bennett Foxp1-mediated programming of limb-innervating motor neurons from mouse and human embryonic stem cells. Nat Commun, 2015-04-14;6(0):6778. 2015-04-14 [PMID: 25868900] (IHC, Mouse)	IHC	Mouse
Gu , Zirong, Imai , Fumiyasu, Kim , In Jung, Fujita , Hiroko, Katayama , Kei ichi, Mori , Kensaku, Yoshihara , Yoshihir, Yoshida , Yutaka Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS ONE, 2015-03-31;10(3):e0121550. 2015-03-31 [PMID: 25826454] (IHC, Mouse)	IHC	Mouse
Li , Renzhong, Wu , Fuguo, Ruonala , Raili, Sapkota , Darshan, Hu , Zihua, Mu , Xiuqian Isl1 and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cells. PLoS ONE, 2014-03-18;9(3):e92105. 2014-03-18 [PMID: 24643061] (ChIP, Mouse)	ChIP	Mouse
Gasimli L, Hickey AM, Yang B et al. Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards mesoderm and endoderm lineages. BBA General Subjects. 1/1/2014 [PMID: 24412195]
Chen J, Fu R, Cui Y, Li Y, Pan J, Liu J, Luo H, Yin J, Li D, Cui S LIM-homeodomain transcription factor Isl-1 mediates the effect of leptin on insulin secretion in mice. J Biol Chem, 2013-03-15;288(17):12395-405. 2013-03-15 [PMID: 23504315] (IHC, Western Blot, Mouse)	IHC, Western Blot	Mouse
Hazen VM, Phan KD, Hudiburgh S, Butler SJ Inhibitory Smads differentially regulate cell fate specification and axon dynamics in the dorsal spinal cord. Dev. Biol., 2011-06-22;356(2):566-75. 2011-06-22 [PMID: 21718693] (IHC, Chicken)	IHC	Chicken
Yau WW, Tang MK, Chen E Cardiogenol C can induce Mouse Hair Bulge Progenitor Cells to Transdifferentiate into Cardiomyocyte-like Cells. Proteome Sci, 2011-01-19;9(1):3. 2011-01-19 [PMID: 21247432] (ICC, Mouse)	ICC	Mouse
Karumbayaram S, Novitch BG, Patterson M, Umbach JA, Richter L, Lindgren A, Conway AE, Clark AT, Goldman SA, Plath K, Wiedau-Pazos M, Kornblum HI, Lowry WE Directed differentiation of human-induced pluripotent stem cells generates active motor neurons. Stem Cells, 2009-04-01;27(4):806-11. 2009-04-01 [PMID: 19350680] (IHC, Human)	IHC	Human
Dimitriadis G, Maratou E, Boutati E IGF-I increases the recruitment of GLUT4 and GLUT3 glucose transporters on cell surface in hyperthyroidism. Eur. J. Endocrinol., 2008-03-01;158(3):361-6. 2008-03-01 [PMID: 18299470] (ICC, Mouse)	ICC	Mouse
Show All 36 Publications. Collapse Publications.

Gene Symbol	ISL1
Uniprot	P61371()