Species: Hu, Bv, Pm
Applications: WB, Flow, ICC/IF, IHC, KO
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Pm
Applications: WB, ELISA, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
The Trans-Golgi network integral membrane protein 2 (TGOLN2) was designated TGN46 based on the predicted molecular mass (46kDa). However, TGN46 is a heavily glycosylated protein, so its molecular weight is often detected at a 110-120kDa.
The TGN46 protein is widely expressed. It may be involved in regulating membrane traffic to and from trans-Golgi network, and has been reported as the best available marker for human trans-Golgi network.
TGN46 contains a luminal domain, a membrane-spanning domain, and a cytoplasmic domain. The membrane-spanning and cytoplasmic domains contain the retention and retrieval signals, respectively, for localization in the TGN.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human |
Product By Gene ID |
10618 |
Alternate Names |
- TGN 46
- TGN 48
- TGN 51
- TGN38 homolog
- TGN38
- TGN-38
- TGN46
- TGN-46
- TGN48
- TGN51
- TGOLN 2
- TGOLN2
- trans golgi network 38
- trans golgi network 46
- Trans Golgi network integral membrane protein 2 [Precursor]
- Trans Golgi network integral membrane protein 2
- Trans Golgi network protein (46 48 51kD isoforms)
- Trans golgi network protein 2
- Trans Golgi network protein TGN51
- Trans-Golgi network integral membrane protein 2
- Trans-Golgi network protein 2
- Trans-Golgi network protein TGN51
- TTGN 2
- TTGN2
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