Caspase 6, also known as Apoptotic protease Mch-2, belongs to the peptidase C14A family. It functions as a downstream enzyme in the caspase activation cascade and is responsible for the execution of apoptosis. Its overexpression promotes programmed cell death.
Diseases associated with CASP6 include thoracic cancer and myocardial infarction. Among its related super-pathways are DR3 Signaling and Apoptosis and the survival FAS signaling cascade.
