Western Blot: Musashi-1 Antibody [NB100-1759] - Detection of Musashi-1 protein in 10 ug of rat neural stem cell lysate (lane 1) and normal human brain lysate (lane 2) with Musashi-1 antibody NB100-1759 at a dilution of ...read more
Immunocytochemistry/ Immunofluorescence: Musashi-1 Antibody [NB100-1759] - Staining with Musashi polyclonal antibody (1:100 dilution) shows Musashi (green) staining on neural rosettes (human). Nuclei are counterstained ...read more
Immunocytochemistry/ Immunofluorescence: Musashi-1 Antibody [NB100-1759] - Musashi-positive cells stained with Musashi antibody (1:150 dilution) in the ventricular zone of E14.5 mouse medulla. Image taken at 200x ...read more
Reacts with human, rat, and mouse Musashi 1 protein.
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified
Alternate Names for Musashi-1 Antibody - BSA Free
MSI1
Musashi (Drosophila) homolog 1
musashi homolog 1 (Drosophila)
Musashi1
Musashi-1
RNA-binding protein Musashi homolog 1
Background
Musashi1, a neural RNA-binding protein, plays an important role in regulating cell differentiation in precursor cells. Musashi-1 (Msi-1) has been shown to increase the accumulation of tau isoforms in intracellular inclusions in dementia. It may play a role in the pathogenesis of various neurodegenerative disorders. Musashi1 has also been detected in human tumor tissues such as gliomas and melanomas, suggesting its involvement in cancer development. Msi-1 also appears to play be an vital role in the development of several types of carcinoma such as human hepatoma, and may be a useful molecular marker for tumor detection.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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