Recombinant Human Stathmin 1 His Protein

Stathmin is a ubiquitous phosphoprotein proposed to play a general role as an intracellular relay integrating diverse regulatory signals of the cellular environment. Also, Stathmin protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. The role of Stathmin in regulation of the cell cycle causes it to be an oncoprotein (Oncoprotein 18, op18). When Stathmin is mutated and not functioning properly, this protein can cause uncontrolled cell proliferation. Recombinant human Stathmin protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Showing Publications 1 - 2 of 2.

Publications using NBC1-21276	Applications	Species
Chen G, Chen X, Sukumar A et al. TGFbeta receptor I transactivation mediates stretch-induced Pak1 activation and CTGF upregulation in mesangial cells. J Cell Sci 2013-06-18 [PMID: 23781022]
Sukumar A. The Role of p21-Activated Kinase in Mechanical Stress-Induced Connective Tissue Growth Factor Upregulation in Mesangial Cells. McMaster University. 2011-10-01

Array NBC1-21276

• Stathmin 1 Antibodies
• Stathmin 1 Lysates
• Stathmin 1 Proteins