SSBP1 Antibody

The single-stranded-DNA-binding proteins (SSBs) are essential for DNA function in prokaryotic and eukaryotic cells, mitochondria, phages and viruses. Mitochondrial single-stranded DNA-binding protein (mtSSB or SSBP1) is necessary for mtDNA replication. SSBP1 is a homotetramer that binds preferentially and cooperatively to single-stranded DNA. It is localized to the mitochondria in normal and neoplastic human tissue of different origin, function, and differentiation, and is likely involved in mitochondrial DNA replication.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 4 applications: IB, ICC/IF, IHC-P, WB.

Showing Publications 1 - 7 of 7.

Publications using NBP1-80720	Applications	Species
Atzori MG, Ceci C, Ruffini F Et al. The Anti-Vascular Endothelial Growth Factor Receptor 1 (VEGFR-1) D16F7 Monoclonal Antibody Inhibits Melanoma Adhesion to Soluble VEGFR-1 and Tissue Invasion in Response to Placenta Growth Factor Cancers (Basel) 2022-11-26 [PMID: 36428669] (IHC-P) Details: Citation using the HRP version of this antibody.	IHC-P
Tian HP, Sun YH, He L et al. Single-Stranded DNA-Binding Protein 1 Abrogates Cardiac Fibroblast Proliferation and Collagen Expression Induced by Angiotensin II. Int Heart J. 2018-10-25 [PMID: 30369577]
Liu H, He Z, April SL et al. Biochemical re-programming of human dermal stem cells to neurons by increasing mitochondrial membrane potential Cell Death Differ. 2018-08-28 [PMID: 30154448] (ICC/IF, Human)	ICC/IF	Human
Zurita Rendon O, Shoubridge E. LONP1 is required for maturation of a subset of mitochondrial proteins and its loss elicits an integrated stress response bioRxiv 2018-04-23 [PMID: 30061372] (IB, Human)	IB	Human
Torralba D, Baixauli F, Villarroya-Beltri C et al. Priming of dendritic cells by DNA-containing extracellular vesicles from activated T cells through antigen-driven contacts. Nat Commun 2018-07-09 [PMID: 29985392] (ICC/IF, Human)	ICC/IF	Human
Rajala N, Hensen F, Wessels HJ et al. Whole Cell Formaldehyde Cross-Linking Simplifies Purification of Mitochondrial Nucleoids and Associated Proteins Involved in Mitochondrial Gene Expression. PLoS One 2015-01-01 [PMID: 25695250] (WB)	WB
Nicolas A, Alazard-Dany N, Biollay C et al. Identification of rep-associated factors in herpes simplex virus type 1-induced adeno-associated virus type 2 replication compartments. J Virol 2010-09-01 [PMID: 20573815]

Array NBP1-80720

• SSBP1 Antibodies
• SSBP1 Lysate
• SSBP1 Proteins