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Pax3 Antibody (PAX3/8426) [Alexa Fluor® 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
PAX3/8426
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 350

Order Details

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Pax3 Antibody (PAX3/8426) [Alexa Fluor® 350] Summary

Immunogen
Recombinant human Pax3 protein
Localization
Nucleus.
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
PAX3
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Pax3 Antibody (PAX3/8426) [Alexa Fluor® 350]

  • CDHS
  • HUP2
  • HUP2MGC120384
  • MGC120381
  • MGC120382
  • MGC120383
  • MGC134778
  • paired box 3
  • paired box gene 3 (Waardenburg syndrome 1)
  • paired box homeotic gene 3
  • paired box protein Pax-3
  • paired domain gene 3
  • paired domain gene HuP2
  • Pax3
  • Waardenburg syndrome 1
  • WS1
  • WS3

Background

PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These proteins play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional Pax3 Products

Array NBP3-20757AF350

Research Areas for Pax3 Antibody (NBP3-20757AF350)

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Blogs on Pax3.

FOXO1/FKHR (fork head in Rhabdomyosarcoma)
FOXO1 belongs to the very large Forkhead family of transcription factors which contain a conserved distinct DNA-binding domain known as the Forkhead Box, or FOX. The Forkhead domain is a 100 amino acid long motif capable of binding and bending DNA,...  Read full blog post.

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Bioinformatics

Gene Symbol PAX3