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Notch-3 Antibody (603532) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
603532
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB1559U-100UG
Alexa Fluor 405
FAB1559V-100UG
Alexa Fluor 488
FAB1559G-100UG
Alexa Fluor 532
FAB1559X
Alexa Fluor 594
FAB1559T-100UG
Alexa Fluor 647
FAB1559R-100UG
Alexa Fluor 700
FAB1559N-100UG
Alexa Fluor 750
FAB1559S-100UG
Allophycocyanin/Cy7
FAB1559APCCY7
Biotin
FAB1559B
CoraFluor 1
FAB1559CL1
DyLight 350
FAB1559D
DyLight 405
FAB1559E
DyLight 488
FAB1559K
DyLight 550
FAB1559L
DyLight 594
FAB1559M
DyLight 650
FAB1559W
DyLight 680
FAB1559Y
DyLight 755
FAB1559Z
FITC
FAB1559F
HRP
FAB1559H
Janelia Fluor 525
FAB1559JF525
Janelia Fluor 585
FAB1559JF585
Janelia Fluor 635
FAB1559JF635
Janelia Fluor 646
FAB1559J
Janelia Fluor 669
FAB1559JF669
PE/Atto594
FAB1559PEATT594
PE/Cy5.5
FAB1559PECY55
PE/Cy7
FAB1559PECY7
PerCP
FAB1559C
Phycoerythrin
FAB6870P
Unconjugated
MAB1559
mFluor Violet 450 SE
FAB1559MFV450
mFluor Violet 500 SE
FAB1559MFV500
mFluor Violet 610 SE
FAB1559MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB1559
Carrier Free
FAB6870P
Carrier Free
MAB1559
Carrier Free
MAB1559-SP
Carrier Free
FAB1559V-100UG
Carrier Free
FAB1559U-100UG
Carrier Free
FAB1559T-100UG
Carrier Free
FAB1559S-100UG
Carrier Free
FAB1559R-100UG
Carrier Free
FAB1559N-100UG
Carrier Free
FAB1559G-100UG
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Notch-3 Antibody (603532) [Janelia Fluor® 549] Summary

Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Notch-3
Ala40-Glu467
Accession # Q9UM47
Specificity
Detects human Notch-3 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) Notch-3 ICD (aa 2195-2321), rhNotch-1, rhNotch-1 ICD (aa 2251-2556), rhNotch-2, rhNotch-2 ICD (aa 2063-2413), rhNotch-4, rhNotch-4 ICD (aa 1778-2003), recombinant mouse Notch-3, or recombinant rat DLL1 is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
NOTCH3
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Notch-3 Antibody (603532) [Janelia Fluor® 549]

  • CADASIL
  • CASILneurogenic locus notch homolog protein 3
  • Notch (Drosophila) homolog 3
  • notch 3Notch homolog 3 (Drosophila)
  • Notch homolog 3
  • Notch3
  • Notch-3

Background

The NOTCH3 gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NOTCH3