NLRP11 Antibody

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP11, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: ICC/IF, WB.

Showing Publication 1 - 1 of 1.

Publication using NBP1-92186	Applications	Species
Gangopadhyay A, Devi S, Tenguria S et al. NLRP3 licenses NLRP11 for inflammasome activation in human macrophages Nature immunology 2022-05-27 [PMID: 35624206] (ICC/IF, WB, Human)	ICC/IF, WB	Human

Array NBP1-92186

• NLRP11 Antibodies
• NLRP11 Lysate
• NLRP11 Proteins