![Melan-A/MART-1 Antibody (M2-7C10) [mFluor Violet 500 SE] - Vial of mFluor Violet 500 conjugated antibody. mFluor Violet 500 is optimally excited at 410 nm by the Violet laser (405 nm) and has an emission maximum of 501 nm.](http://images.novusbio.com/fullsize/nbp2-33148mfv500_mouse-melan-a-mart-1-mab-m2-7c10-mfluor-violet-500-se-57202313215996.png "Melan-A/MART-1 Antibody (M2-7C10) [mFluor Violet 500 SE] - Vial of mFluor Violet 500 conjugated antibody. mFluor Violet 500 is optimally excited at 410 nm by the Violet laser (405 nm) and has an emission maximum of 501 nm.")
| Reactivity | Hu, Eq, Rt(-)Species Glossary |
| Applications | WB, Flow, IHC |
| Clone | M2-7C10 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | mFluor Violet 500 SE |
| Immunogen | Recombinant Melan-A/MART-1 protein (Uniprot: Q16655) |
| Localization | Cytoplasmic |
| Marker | Melanoma Marker |
| Specificity | This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This monoclonal antibody labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. |
| Isotype | IgG2b Lambda |
| Clonality | Monoclonal |
| Host | Mouse |
| Gene | MLANA |
| Purity | Protein A or G purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Application Notes | Optimal dilution of this antibody should be experimentally determined. |
| Storage | Store at 4C in the dark. |
| Buffer | 50mM Sodium Borate |
| Preservative | 0.05% Sodium Azide |
| Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for Melan-A/MART-1 Antibody (NBP2-33148MFV500)Find related products by research area.
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| Gene Symbol | MLANA |
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