Melan-A/MART-1 Antibody (A103) - Azide and BSA Free Summary
Immunogen |
Recombinant human Melan-A/MART-1. [Uniprot# Q16655] |
Isotype |
IgG1 Kappa |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
MLANA |
Purity |
Protein G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- CyTOF-ready
- ELISA
- Flow Cytometry
- Immunocytochemistry/ Immunofluorescence reported in scientific literature (PMID 27565163)
- Immunohistochemistry 1:100
- Immunohistochemistry-Frozen 1:100
- Immunohistochemistry-Paraffin
- Western Blot 2 ug/ml
|
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
No Preservative |
Concentration |
1 mg/ml |
Purity |
Protein G purified |
Alternate Names for Melan-A/MART-1 Antibody (A103) - Azide and BSA Free
Background
Melan-A/MART-1, also known as MLANA or melanoma antigen recognized by T-cells 1, is expressed exclusively in retina, melanoma, and melanocyte cells. Melan-A interacts with GPR143, ensuring its stability, as well as with PMEL. The interaction between Melan-A and PMEL is crucial to the development of stage II melanosomes, which are organelles that contain and store melanin. Melan-A is found in the membranes of the Golgi apparatus, endoplasmic reticulum, as well as the cell membrane itself. Melan-A's expression on the exterior of melanoma cells are key in the recognition and subsequent lysis of these cells by cytolytic T-Lymphocytes, giving Melan-A a large role in cancer research pertaining to melanomas.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for Melan-A/MART-1 Antibody (NBP2-80846) (0)
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Product General Protocols
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FAQs for Melan-A/MART-1 Antibody (NBP2-80846) (0)
Secondary Antibodies
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Isotype Controls
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