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Langerin/CD207 Antibody (923B7) [Alexa Fluor® 488]

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Product Details

Summary
Reactivity Hu, Mu, Rt, PoSpecies Glossary
Applications Flow, ICC/IF
Clone
923B7
Clonality
Monoclonal
Host
Rat
Conjugate
Alexa Fluor 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 546
DDX0373A546-100
Alexa Fluor 647
DDX0373A647-100
Unconjugated
DDX0373P-100
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Langerin/CD207 Antibody (923B7) [Alexa Fluor® 488] Summary

Immunogen
Langerin/CD207 was used as immunogen.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
CD207
Purity
Ion exchange chromatography
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
  • Immunocytochemistry/ Immunofluorescence 1:10-1:2000

Reactivity Notes

Human, Mouse, Rat, Porcine

Packaging, Storage & Formulations

Storage
Store at -20C in the dark. Avoid freeze-thaw cycles.
Buffer
PBS and 50% Glycerol
Preservative
No Preservative
Purity
Ion exchange chromatography

Notes

This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.

Alternate Names for Langerin/CD207 Antibody (923B7) [Alexa Fluor® 488]

  • CD207 antigen
  • CD207 antigen, langerin
  • CD207 molecule, langerin
  • CD207
  • CLEC4KLangerhans cell specific c-type lectin
  • C-type lectin domain family 4 member K
  • C-type lectin domain family 4, member K
  • Langerin

Background

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Langerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Langerin/CD207
Antibody (923B7) [Ale ...
DDX0373A488-100
Langerin/CD207 Antibody (923B7) [Alexa Fluor® 488]
Species: Hu, Mu, Rt, Po
Applications: Flow, ICC/IF

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Video Protocols

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Bioinformatics

Gene Symbol CD207