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KIR2DS1/CD158h Antibody (1127B) [Unconjugated]

 (3 Publications)
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Human peripheral blood mononuclear cells (PBMCs) from different donors (A and B) were stained with Rabbit Anti-Human KIR2DS1/CD158h Monoclonal Antibody (Catalog # MAB8887) followed by Allophycocyanin-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog # F0111) and Mouse Anti-Human KIR2DL1/KIR2DS5 Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB1844F). Cells were gated on CD56 with Mouse Anti-Human NCAM‑1/CD56 PE‑conjugated Monoclonal Antibody (Catalog # FAB2408P, not shown).
Human peripheral blood mononuclear cells (PBMCs) from different donors (A and B) were stained with Rabbit Anti-Human KIR2DS1/CD158h Monoclonal Antibody (Catalog # MAB8887) followed by Allophycocyanin-conjugated ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
1127B
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB8887U-100UG
Alexa Fluor 405
FAB8887V-100UG
Alexa Fluor 488
FAB8887G-025
Alexa Fluor 532
FAB8887X
Alexa Fluor 594
FAB8887T-100UG
Alexa Fluor 647
FAB8887R-100
Alexa Fluor 647
FAB8887R-025
Alexa Fluor 700
FAB8887N-100UG
Alexa Fluor 750
FAB8887S-100UG
Allophycocyanin
FAB8887A
Allophycocyanin/Cy7
FAB8887APCCY7
Biotin
FAB8887B
CoraFluor 1
FAB8887CL1
DyLight 350
FAB8887D
DyLight 405
FAB8887E
DyLight 488
FAB8887K
DyLight 550
FAB8887L
DyLight 594
FAB8887M
DyLight 650
FAB8887W
DyLight 680
FAB8887Y
DyLight 755
FAB8887Z
FITC
FAB8887F
HRP
FAB8887H
Janelia Fluor 525
FAB8887JF525
Janelia Fluor 549
FAB8887I
Janelia Fluor 585
FAB8887JF585
Janelia Fluor 635
FAB8887JF635
Janelia Fluor 646
FAB8887J
Janelia Fluor 669
FAB8887JF669
PE/Atto594
FAB8887PEATT594
PE/Cy5.5
FAB8887PECY55
PE/Cy7
FAB8887PECY7
PerCP
FAB8887C
Phycoerythrin
FAB8887P-100
Phycoerythrin
FAB8887P-025
mFluor Violet 450 SE
FAB8887MFV450
mFluor Violet 500 SE
FAB8887MFV500
mFluor Violet 610 SE
FAB8887MFV610
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB8887-SP
Carrier Free
FAB8887G-025
Carrier Free
FAB8887P-025
Carrier Free
FAB8887R-025
Carrier Free
FAB8887V-100UG
Carrier Free
FAB8887U-100UG
Carrier Free
FAB8887T-100UG
Carrier Free
FAB8887S-100UG
Carrier Free
FAB8887N-100UG
Carrier Free
FAB8887R-100
Carrier Free
FAB8887P-100
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KIR2DS1/CD158h Antibody (1127B) [Unconjugated] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
HEK293 human embryonic kidney cell line transfected with human KIR2DS1/CD158h
Met1-His245
Accession # Q14954
Specificity
Detects human KIR2DS1/CD158h in flow cytometry. Clone 1127B recognizes KIR2DS1 and some alleles of KIR2DL1, both members of the killer cell immunoglobulin-like receptor (KIR) family. Because Clone 1127B displays partial cross-reactivity with KIR2DL1, co-staining with Mouse Anti-Human KIR2DL1 Clone 143211 (Catalog # FAB1844F) is recommended.
Source
N/A
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
KIR2DS1
Purity Statement
Protein A or G purified from cell culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25 ug/10^6 cells
Publications
Read Publications using MAB8887.

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
Sodium Azide
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for KIR2DS1/CD158h Antibody (1127B) [Unconjugated]

  • killer cell immunoglobulin-like receptor 2DS1
  • CD158a
  • CD158h
  • EB6ActI
  • killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
  • KIR2DS1
  • p50.1

Background

The KIRs comprise a family of 14 polymorphic and homologous activating and inhibitory receptors expressed primarily on CD56dim NK cells. KIR2DS1 is an activating receptor with high homology to the inhibitory receptor KIR2DL1. Both KIR2DL1 and KIR2DS1 bind to HLA-C alleles containing the C2 epitope. KIR2DS1 and KIR2DL1 expression regulates NK cell licensing and activation in a number of immune contexts.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for KIR2DS1/CD158h Antibody (MAB8887)(3)


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Bioinformatics

Gene Symbol KIR2DS1
Uniprot