Immunocytochemistry/ Immunofluorescence: HOXD4 Antibody [NBP2-49631] - Staining of human cell line SK-MEL-30 shows localization to nucleoplasm. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: HOXD4 Antibody [NBP2-49631] - Staining of human epididymis shows moderate nuclear positivity in glandular cells.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for HOXD4 Antibody
HHO.C13
homeo box D4
homeobox D4
Homeobox protein HHO.C13
Homeobox protein Hox-4B
Homeobox protein Hox-5.1
homeobox protein Hox-D4
HOX4
Hox-4.2
Hox-4.2, mouse, homolog of homeo box X
HOX4BHOX-5.1
Background
HOXD4 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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