HGK/MAP4K4 Antibody

MAP4K4 is encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 4 applications: ICC/IF, IF/IHC, IHC-P, WB.

Showing Publications 1 - 2 of 2.

Publications using NBP1-84663	Applications	Species
Huang H, Kuang X, Zou Y et al. MAP4K4 is involved in the neuronal development of retinal photoreceptors Experimental eye research 2023-06-07 [PMID: 37290629] (ICC/IF, IHC-P, WB, Mouse)	ICC/IF, IHC-P, WB	Mouse
Rizzardi AE, Rosener NK, Koopmeiners JS et al. Evaluation of protein biomarkers of prostate cancer aggressiveness. BMC Cancer 2014-04-05 [PMID: 24708576] (IF/IHC, Human)	IF/IHC	Human

Array NBP1-84663

• HGK/MAP4K4 Antibodies
• HGK/MAP4K4 Lysate
• HGK/MAP4K4 Protein