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HGK/MAP4K4 Antibody [Janelia Fluor® 635]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 635

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-74630AF350
Alexa Fluor 405
NB100-74630AF405
Alexa Fluor 488
NB100-74630AF488
Alexa Fluor 532
NB100-74630AF532
Alexa Fluor 594
NB100-74630AF594
Alexa Fluor 647
NB100-74630AF647
Alexa Fluor 700
NB100-74630AF700
Alexa Fluor 750
NB100-74630AF750
Allophycocyanin
NB100-74630APC
Biotin
NB100-74630B
CoraFluor 1
NB100-74630CL1
DyLight 350
NB100-74630UV
DyLight 405
NB100-74630V
DyLight 488
NB100-74630G
DyLight 550
NB100-74630R
DyLight 594
NB100-74630DL594
DyLight 650
NB100-74630C
DyLight 680
NB100-74630FR
DyLight 755
NB100-74630IR
FITC
NB100-74630F
HRP
NB100-74630H
Janelia Fluor 525
NB100-74630JF525
Janelia Fluor 549
NB100-74630JF549
Janelia Fluor 585
NB100-74630JF585
Janelia Fluor 646
NB100-74630JF646
Janelia Fluor 669
NB100-74630JF669
PE
NB100-74630PE
PerCP
NB100-74630PCP
Unconjugated
NB100-74630
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HGK/MAP4K4 Antibody [Janelia Fluor® 635] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 850 and 900 of human MAPK/ERK kinase kinase kinase 4 (hepatocyte progenitor kinase-like/germinal center kinase-like kinase) using the numbering given in entry AAO32626.1 (GeneID 94
Predicted Species
Mouse (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MAP4K4
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for HGK/MAP4K4 Antibody [Janelia Fluor® 635]

  • EC 2.7.11
  • EC 2.7.11.1
  • FLH21957
  • FLJ10410
  • hepatocyte progenitor kinase-like/germinal center kinase-like kinase
  • HGK
  • HGKFLJ20373
  • HPK/GCK-like kinase HGK
  • KIAA0687
  • MAP4K4
  • MAPK/ERK kinase kinase kinase 4
  • MEK kinase kinase 4
  • MEKKK 4
  • MEKKK4
  • mitogen-activated protein kinase kinase kinase kinase 4
  • Nck-interacting kinase
  • NIKFLJ90111

Background

MAP4K4 is encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MAP4K4