HGK/MAP4K4 Antibody (4A5)

This product is produced by and distributed for Abnova, a company based in Taiwan.

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 2 of 2.

Publications using H00009448-M07	Applications	Species
Ma M, Baumgartner M. Intracellular Theileria annulata Promote Invasive Cell Motility through Kinase Regulation of the Host Actin Cytoskeleton. PLoS Pathog. 2014-03-13 [PMID: 24626571]
Ma M, Baumgartner M. Filopodia and Membrane Blebs Drive Efficient Matrix Invasion of Macrophages Transformed by the Intracellular Parasite Theileria annulata. PLoS One. 2013-09-24 [PMID: 24086576]

Array H00009448-M07

• HGK/MAP4K4 Antibodies
• HGK/MAP4K4 Lysate
• HGK/MAP4K4 Proteins