GAD1/GAD67 Antibody

Chicken products cannot be exported to Canada.

Purification Notes
After repeated injections into the hens, immune eggs were collected, and the IgY fractions were purified from the yolks. These IgY fractions were then affinity-purified using a peptide column, the concentrations of the eluate adjusted to 100 ug/ml, and the preparation was filter-sterilized through a 0.45 um filter.

Storage Notes
Store at 4C in the dark. Under these conditions, the antibodies should have a shelf life of at least 12 months (provided they remain sterile). Do not freeze these antibodies unless you want to store them for longer periods of time. Note, however, that each time an antibody preparation is frozen, about half of its binding activity is lost.

Glutamic Acid Decarboxylase (GAD) catalyzes the conversion of glutamate to gamma-aminobutyric acid (GABA). There are two known forms of GAD; GAD65 (65 kDa) and GAD67 (67 kDa) that are encoded by two different genes and appear to have distinct intraneuronal distribution in the brain. This antibody reacts with GAD67 and is predicted to react with GAD65.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Rat.

We have publications tested in 2 applications: IF/IHC, WB.

Showing Publications 1 - 6 of 6.

Publications using NBP1-02161	Applications	Species
Scheuer T, Endesfelder S, Auf dem Brinke E et al. Neonatal Oxidative Stress Impairs Cortical Synapse Formation and GABA Homeostasis in Parvalbumin-Expressing Interneurons Oxidative Medicine and Cellular Longevity 2022-05-25 [PMID: 35663195] (WB)	WB
Franco-GarcIa A, FernAndez-GOmez FJ, GOmez-Murcia V et al. Molecular Mechanisms Underlying the Retrieval and Extinction of Morphine Withdrawal-Associated Memories in the Basolateral Amygdala and Dentate Gyrus Biomedicines 2022-03-02 [PMID: 35327388] (IF/IHC, Rat)	IF/IHC	Rat
Guerrero-Bautista R, Franco-Garcia A, Hidalgo J, et al. Distinct regulation of dopamine D3 receptor in the basolateral amygdala and dentate gyrus during the reinstatement of cocaine CPP induced by drug priming and social stress Int J Mol Sci 2021-04-03 [PMID: 33803578]
Arcidiacono B, Chiefari E, Foryst-Ludwig A et al. Obesity-related hypoxia via miR-128 decreases insulin-receptor expression in human and mouse adipose tissue promoting systemic insulin resistance EBioMedicine 2020-07-27 [PMID: 32739259] (WB, Human)	WB	Human
Guerrero-Bautista R, Franco-GarcIa A, Hidalgo JM et al. Blockade of D3 receptor prevents changes in DAT and D3R expression in the mesolimbic dopaminergic circuit produced by social stress- and cocaine prime-induced reinstatement of cocaine-CPP J. Psychopharmacol. (Oxford) 2020-07-10 [PMID: 32648812]
Valladolid-Acebes I, Merino B, Principato A et al. High fat diets induce changes in hippocampal glutamate metabolism and neurotransmission. American Journal of Physiology. Endocrinology and Metabolism. 2011-11-22 [PMID: 22114023]

Array NBP1-02161

• GAD1/GAD67 Antibodies
• GAD1/GAD67 ELISA Kits
• GAD1/GAD67 Lysate
• GAD1/GAD67 Proteins