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FosB/G0S3 Antibody (83B1138) [DyLight 650]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
83B1138
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 650

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-56530AF350
Alexa Fluor 405
NB100-56530AF405
Alexa Fluor 488
NB100-56530AF488
Alexa Fluor 532
NB100-56530AF532
Alexa Fluor 594
NB100-56530AF594
Alexa Fluor 647
NB100-56530AF647
Alexa Fluor 700
NB100-56530AF700
Alexa Fluor 750
NB100-56530AF750
Biotin
NB100-56530B
DyLight 350
NB100-56530UV
DyLight 405
NB100-56530V
DyLight 488
NB100-56530G
DyLight 550
NB100-56530R
DyLight 594
NB100-56530DL594
DyLight 680
NB100-56530FR
DyLight 755
NB100-56530IR
FITC
NB100-56530F
HRP
NB100-56530H
Janelia Fluor 549
NB100-56530JF549
Janelia Fluor 646
NB100-56530JF646
Unconjugated
NB100-56530
mFluor Violet 450 SE
NB100-56530MFV450
mFluor Violet 500 SE
NB100-56530MFV500
mFluor Violet 610 SE
NB100-56530MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB100-56530
BSA Free
NB100-56530
BSA Free
NB100-56530SS
Azide Free
NBP2-33219
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FosB/G0S3 Antibody (83B1138) [DyLight 650] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
This antibody was generated by immunizing mice with a synthetic peptide corresponding to amino acids 2-15 of human FosB.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
FOSB
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for FosB/G0S3 Antibody (83B1138) [DyLight 650]

  • activator protein 1
  • AP-1
  • DKFZp686C0818
  • FBJ murine osteosarcoma viral oncogene homolog B
  • FosB
  • G0S3
  • G0S3G0/G1 switch regulatory protein 3
  • GOS3
  • GOSB
  • MGC42291
  • oncogene FOS-B
  • protein fosB

Background

Fos and Jun dimerize to form Activator Protein-1 (AP-1), a transcriptional factor that binds to the 12-O-tetradecanoylphorbol 13-acetate (TPA) response element (TRE) of several cellular and viral genes including human collagenase, metallothionein IIa, stromelysin, interleukin 2, SV40 and polyoma. Fos and Jun contain the 'leucine-zipper' motif that allows for dimerization and an adjacent basic domain required for biological activity. The functionally active form of Fos is in a heterodimer with a member of the Jun family. While Jun family members can form functional homodimers, studies indicate that Fos family members do not self-associate and therefore do not bind DNA on their own. The various dimers differ in their ability to transactivate AP-1 dependent genes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FOSB