FIZZ1/RELM alpha Antibody - BSA Free

A family of resistin-like molecules (RELMs) has been identified in rodents and humans. Resistin is a hormone produced by fat cells. RELMalpha is a secreted protein that has a restricted tissue distribution with highest levels in adipose tissue. Another family member, RELMbeta, is a secreted protein expressed only in the gastrointestinal tract, particularly the colon, in both mouse and human. RELMbeta gene expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation. Resistin and the RELMs share a cysteine composition and other signature features. Thus, the RELMs together with resistin comprise a class of tissue-specific signaling molecules.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: WB.

Showing Publication 1 - 1 of 1.

Publication using NBP2-29355	Applications	Species
Lin L, Hu K. Tissue-type plasminogen activator modulates macrophage M2 to M1 phenotypic change through annexin A2-mediated NF-kappa B pathway Oncotarget 2017-10-20 [PMID: 29152144] (WB, Mouse)	WB	Mouse

Images	Ratings	Applications	Species	Date	Details
Enlarge	4 reviewed by: Lisha Joshi	WB	Mouse	06/10/2019	View Summary Application Western Blot Sample Tested BV2 microglia cells Species Mouse Lot 51120 Comments Comments The antibody was used in order to study the effects of lysophosphatidic acid (LPA) on microglia polarization state. It was used in a dilution of 1:500. Using a dilution 1:1000 didn't work so well.
Enlarge	5 reviewed by: Joanna Plastira	ICC	Mouse	06/07/2019	View Summary Application Immunocytochemistry Sample Tested BV2 microglia cells Species Mouse Lot 51120 Comments Comments The antibody was used at a concentration 1:100. Having used the antibody for both ICC and WB, I would say that for ICC it worked perfectly. In WB there were some problems with the detection but still a very good antibody to use for both methods.
Enlarge	4 reviewed by: Joanna Plastira	WB	Mouse	06/07/2019	View Summary Application Western Blot Sample Tested BV2 microglia cell lysate,Murine microglia cell lysate Species Mouse Lot 51120 Comments Comments The antibody was used in a concentration 1:500 in order to detect changes in expression levels in BV2 microglia cells.

Array NBP2-29355

• FIZZ1/RELM alpha Antibodies