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Fc gamma RI/CD64 Antibody (008) [mFluor Violet 610 SE]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA, IHC
Clone
008
Clonality
Monoclonal
Host
Rabbit
Conjugate
mFluor Violet 610 SE

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Fc gamma RI/CD64 Antibody (008) [mFluor Violet 610 SE] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Fc gamma RI/CD64 (Accession#: NP_034316.1; Met 1-Pro 297).
Specificity
Has cross-reactivity in ELISA with:

Mouse FCGR4
Mouse FCGR2B
Human CD16a
Human CD16b
Human CD32a
Human CD32b
Human CD64
Mouse FCGR3
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
FCGR1A
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Fc gamma RI/CD64 Antibody (008) [mFluor Violet 610 SE]

  • CD64 antigen
  • CD64
  • CD64a
  • Fc fragment of IgG, high affinity Ia, receptor (CD64)
  • Fc gamma RI
  • FCG1
  • Fc-gamma receptor I B2
  • Fc-gamma RI
  • Fc-gamma RIA
  • FcgammaRIa
  • FCGR1
  • FcgRI
  • FcgRIA
  • FCRI
  • FcRIA
  • FLJ18345
  • high affinity Ia, receptor for (CD64)
  • high affinity immunoglobulin gamma Fc receptor I
  • IgG Fc receptor I

Background

CD64 is a 72 kD single chain type I glycoprotein also known as Fc gammaRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN- gamma stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol FCGR1A