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Fc gamma RI/CD64 Antibody (008)

Images

 
Immunohistochemistry-Paraffin: Fc gamma RI/CD64 Antibody (008) [NBP2-90404] - Staining of mouse Fc gamma RI/CD64 in mouse spleen with rabbit monoclonal antibody (1:200). Positive staining was localized to Kupffer cell.
Immunohistochemistry-Paraffin: Fc gamma RI/CD64 Antibody (008) [NBP2-90404] - Staining of mouse Fc gamma RI/CD64 in mouse brain with rabbit monoclonal antibody (1:200). Positive staining was localized to microglia.
Immunohistochemistry-Paraffin: Fc gamma RI/CD64 Antibody (008) [NBP2-90404] - Staining of mouse Fc gamma RI/CD64 in mouse liver with rabbit monoclonal antibody (1:100). Positive staining was localized to Kupffer cell.

Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA, IHC
Clone
008
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Fc gamma RI/CD64 Antibody (008) Summary

Description
This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Fc gamma RI/CD64 (Accession#: NP_034316.1; Met 1-Pro 297).
Specificity
Has cross-reactivity in ELISA with:

Mouse FCGR4
Mouse FCGR2B
Human CD16a
Human CD16b
Human CD32a
Human CD32b
Human CD64
Mouse FCGR3
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
FCGR1A
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:5000-1:10000
  • Immunohistochemistry 1:100-1:500
  • Immunohistochemistry-Paraffin 1:100-1:500

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.2 um filtered solution in PBS
Preservative
No Preservative
Purity
Protein A purified

Alternate Names for Fc gamma RI/CD64 Antibody (008)

  • CD64 antigen
  • CD64
  • CD64a
  • Fc fragment of IgG, high affinity Ia, receptor (CD64)
  • Fc gamma RI
  • FCG1
  • Fc-gamma receptor I B2
  • Fc-gamma RI
  • Fc-gamma RIA
  • FcgammaRIa
  • FCGR1
  • FcgRI
  • FcgRIA
  • FCRI
  • FcRIA
  • FLJ18345
  • high affinity Ia, receptor for (CD64)
  • high affinity immunoglobulin gamma Fc receptor I
  • IgG Fc receptor I

Background

CD64 is a 72 kD single chain type I glycoprotein also known as Fc gammaRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN- gamma stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol FCGR1A