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DLL4 Antibody (447506) [Phycoerythrin]

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HUVEC human umbilical vein endothelial cells were stained with Rat Anti-Human DLL4 PE-conjugated Monoclonal Antibody (Catalog # FAB1506P, filled histogram) or isotype control antibody (Catalog # IC006P, open histogram). View our protocol for Staining Membrane-associated Proteins.
HUVEC human umbilical vein endothelial cells were stained with Rat Anti-Human DLL4 PE-conjugated Monoclonal Antibody (Catalog # FAB1506P, filled histogram) or isotype control antibody (Catalog # IC006P, open histogram). ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
447506
Clonality
Monoclonal
Host
Rat
Conjugate
Phycoerythrin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB1506U-100UG
Alexa Fluor 405
FAB1506V-100UG
Alexa Fluor 488
FAB1506G-100UG
Alexa Fluor 532
FAB1506X
Alexa Fluor 594
FAB1506T-100UG
Alexa Fluor 647
FAB1506R-100UG
Alexa Fluor 700
FAB1506N-100UG
Alexa Fluor 750
FAB1506S-100UG
Allophycocyanin/Cy7
FAB1506APCCY7
Biotin
FAB1506B
CoraFluor 1
FAB1506CL1
DyLight 350
FAB1506D
DyLight 405
FAB1506E
DyLight 488
FAB1506K
DyLight 550
FAB1506L
DyLight 594
FAB1506M
DyLight 650
FAB1506W
DyLight 680
FAB1506Y
DyLight 755
FAB1506Z
FITC
FAB1506F
HRP
FAB1506H
Janelia Fluor 525
FAB1506JF525
Janelia Fluor 549
FAB1506I
Janelia Fluor 585
FAB1506JF585
Janelia Fluor 635
FAB1506JF635
Janelia Fluor 646
FAB1506J
Janelia Fluor 669
FAB1506JF669
PE/Atto594
FAB1506PEATT594
PE/Cy5.5
FAB1506PECY55
PE/Cy7
FAB1506PECY7
PerCP
FAB1506C
Unconjugated
MAB1506
mFluor Violet 450 SE
FAB1506MFV450
mFluor Violet 500 SE
FAB1506MFV500
mFluor Violet 610 SE
FAB1506MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB1506
Carrier Free
MAB1506
Carrier Free
MAB1506-SP
Carrier Free
FAB1506V-100UG
Carrier Free
FAB1506U-100UG
Carrier Free
FAB1506T-100UG
Carrier Free
FAB1506S-100UG
Carrier Free
FAB1506N-100UG
Carrier Free
FAB1506G-100UG
Carrier Free
FAB1506R-100UG
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DLL4 Antibody (447506) [Phycoerythrin] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human DLL4
Ser27-Pro524
Accession # Q9NR61
Specificity
Detects human DLL4 in direct ELISAs.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
DLL4
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DLL4 Antibody (447506) [Phycoerythrin]

  • Delta 4 precursor
  • delta 4
  • delta ligand 4
  • delta4
  • delta-like 4 (Drosophila)
  • delta-like 4 homolog (Drosophila)
  • delta-like 4 homolog
  • delta-like 4 protein
  • delta-like protein 4
  • DLL4
  • Drosophila Delta homolog 4
  • hdelta2
  • MGC126344
  • notch ligand delta-2
  • notch ligand DLL4

Background

Delta-like ligand 4 (DLL4) is a transmembrane protein that contains one DSL domain and eight tandem EGF-like repeats. DLL4 is expressed on arterial endothelial cells where it signals through Notch 1 and Notch 4. DLL4 expression is induced by VEGF and regulates the proliferation of endothelial tip cells during vascular sprouting. DLL4 blockade as well as overexpression can suppress tumor growth by promoting dysregulated angiogenesis. Within the extracellular domain, human DLL4 shares 85% amino acid sequence identity with mouse and rat DLL4.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Flow Cytometry Pref-1/DLK1/FA1 Antibody (211309)
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(6 Publications)
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HES-1 Antibody
(OTI4H1)
NBP1-47791
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GATD3A Antibody
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Immunocytochemistry/ Immunofluorescence GATD3A Antibody (1F5)
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Butyrylcholinesterase/ ...
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Immunohistochemistry-Paraffin Elastase Antibody (CELA3B/1257) - Azide and BSA Free
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Azide and BSA Free
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Applications: WB
Notch-2 Antibody
[Unconjugated]
AF3735
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(6 Publications)
Species: Hu
Applications: IHC, WB

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DLL4
Uniprot