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Connexin 43/GJA1 Antibody (578618) [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
578618
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB7737U-100UG
Alexa Fluor 405
FAB7737V-100UG
Alexa Fluor 488
FAB7737G-100UG
Alexa Fluor 532
FAB7737X
Alexa Fluor 594
FAB7737T-100UG
Alexa Fluor 647
FAB7737R-100UG
Alexa Fluor 700
FAB7737N-100UG
Alexa Fluor 750
FAB7737S-100UG
Allophycocyanin
FAB7737A
Allophycocyanin/Cy7
FAB7737APCCY7
Biotin
FAB7737B
DyLight 350
FAB7737D
DyLight 405
FAB7737E
DyLight 550
FAB7737L
DyLight 594
FAB7737M
DyLight 650
FAB7737W
DyLight 680
FAB7737Y
DyLight 755
FAB7737Z
FITC
FAB7737F
HRP
FAB7737H
Janelia Fluor 549
FAB7737I
Janelia Fluor 646
FAB7737J
PE
FAB7737P
PE/Atto594
FAB7737PEATT594
PE/Cy5.5
FAB7737PECY55
PE/Cy7
FAB7737PECY7
PerCP
FAB7737C
Unconjugated
MAB7737
mFluor Violet 450 SE
FAB7737MFV450
mFluor Violet 500 SE
FAB7737MFV500
mFluor Violet 610 SE
FAB7737MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB7737
Carrier Free
MAB7737
Carrier Free
FAB7737A
Carrier Free
MAB7737-SP
Carrier Free
FAB7737V-100UG
Carrier Free
FAB7737U-100UG
Carrier Free
FAB7737T-100UG
Carrier Free
FAB7737S-100UG
Carrier Free
FAB7737R-100UG
Carrier Free
FAB7737N-100UG
Carrier Free
FAB7737G-100UG
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Connexin 43/GJA1 Antibody (578618) [DyLight 488] Summary

Immunogen
Mouse myeloma cell line NS0 transfected with human Connexin 43/GJA1
Accession # P17302
Specificity
Detects human Connexin 43/GJA1. Stains human Connexin 43/GJA1 transfectants but not irrelevant transfectants in flow cytometry.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
GJA1
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Connexin 43/GJA1 Antibody (578618) [DyLight 488]

  • Connexin 43
  • connexin-43
  • CX43
  • CX43gap junction protein, alpha-like
  • DFNB38
  • Gap junction 43 kDa heart protein
  • gap junction alpha-1 protein
  • gap junction protein, alpha 1, 43kDa (connexin 43)
  • gap junction protein, alpha 1, 43kDa
  • GJA1
  • GJAL
  • HSS
  • ODD
  • ODDD
  • ODOD
  • SDTY3

Background

Connexin 43/GJA1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. GJA1 is the major cardiac gap junction protein, which is thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. GJA1 is targeted by several protein kinases that regulate myocardial cell cell coupling. A related intronless GJA1 pseudogene, GJA1P, has been mapped to chromosome 5.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Blogs on Connexin 43/GJA1.

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Connexin: Bridging the Gap of Intercellular Communication
Connexin 43/GJA1 is a member of the connexin gene family and the most abundant protein component found within gap junctions. Gap junctions are the cell-to-cell contacts that provide direct intercellular communication between cells by regulating back a...  Read full blog post.
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Bioinformatics

Gene Symbol GJA1