CNOT7 Antibody (2F6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 7 of 7.

Publications using H00029883-M01	Applications	Species
Toru S, Miyuki H, Saori N et al. Regulation of CCR4-NOT complex deadenylase activity and cellular responses by MK2-dependent phosphorylation of CNOT2. RNA Biol. 2022-02-06 [PMID: 35129087]
Shohei T, Akiko Y, Haytham M et al. Neuronal XRN1 is required for maintenance of whole-body metabolic homeostasis. iScience. 2021-10-22 [PMID: 34646989]
Yi H, Park J, Ha M et al. PABP Cooperates with the CCR4-NOT Complex to Promote mRNA Deadenylation and Block Precocious Decay. Mol Cell 2018-06-21 [PMID: 29932901]
Sheu-Gruttadauria J, MacRae IJ., et al. Phase Transitions in the Assembly and Function of Human miRISC. Cell 2018-03-16 [PMID: 29576456]
Inoue T, Morita M, Hijikata A et al. CNOT3 contributes to early B cell development by controlling Igh rearrangement and p53 mRNA stability. J Exp Med. 2015-08-03 [PMID: 26238124]
Chekulaeva M, Mathys H, Zipprich JT et al. miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs. Nat Struct Mol Biol. 2011-10-07 [PMID: 21984184]
Marchese FP, Aubareda A, Tudor C et al. MAPKAP Kinase 2 Blocks Tristetraprolin-directed mRNA Decay by Inhibiting CAF1 Deadenylase Recruitment. J Biol Chem. 2010-07-01 [PMID: 20595389]

Array H00029883-M01

• CNOT7 Antibodies
• CNOT7 Lysate
• CNOT7 Protein