CD43/Sialophorin Antibody (290101) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

CD43, also known as Leukosialin and Sialophorin and Ly-48 in mouse, is a 100-105 kDa type I transmembrane sialylated mucin that is expressed on most leukocytes and some tumor cells. Notably, the membrane expression of CD43 seems to be a characteristic of leukocytes, while cytoplasmic expression without membrane insertion occurs in endothelium and select epithelia. While CD43 restricts leukocyte adhesion and modulates T cell activation, these activities are context specific. CD43 can both induce and protect against apoptosis, and can either promote or block cell adhesion. Mature CD43 shows 49% amino (aa) sequence identity between human and mouse.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array MAB20381

• CD43/Sialophorin Antibodies
• CD43/Sialophorin Lysates
• CD43/Sialophorin Proteins
• CD43/Sialophorin Proteins and Enzymes