CD43 is a key glycoprotein of thymocytes and T lymphocytes, which affects the physicochemical properties of the T-cell surface and plays a role in lectin binding. This antibody contains an extended rodlike structure that may protrude above the glycocalyx of the cell, allowing accessibility of multiple glycan chains for binding. During T-cell activation CD43 is actively removed from the T-cell-antigen-presenting cell contact site, thus suggesting CD43's role in negative regulation of the adaptive immune response.
![Binding Activity CD43/Sialophorin [Unconjugated]](http://images.novusbio.com/fullsize2/CD43_9680CD_2150.jpg)
![Binding Activity CD43/Sialophorin [Unconjugated]](http://images.novusbio.com/fullsize2/CD43_9959CD_2045.jpg)
![SDS-PAGE CD43/Sialophorin [Unconjugated]](http://images.novusbio.com/fullsize2/CD43_9959CD_2027.jpg)
![SDS-PAGE CD43/Sialophorin [Unconjugated]](http://images.novusbio.com/fullsize2/11205-cd_recombinant-cynomolgus-monkey-cd43-fc-chimera-protein-cf-sds-page-2862022143945.jpg)