P256 induces aggregation of normal platelets in plasma.
Theoretical MW
135 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using NBP2-50443 in the following applications:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified
Alternate Names for CD41/CD61 Antibody (P256) - BSA Free
CD41 antigen
CD41
CD41BHPA3
GP2Bintegrin alpha-IIb
GPalpha IIb
GPIIb
GTA
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41)
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41B)
ITGAB
platelet fibrinogen receptor, alpha subunit
Platelet membrane glycoprotein IIb
platelet-specific antigen BAK
Background
Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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