Species: Hu
Applications: Flow, IP, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ICC/IF, IHC, IP
Host: Mouse Monoclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: ELISA
Description
Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.
Bioinformatics
| Product By Gene ID |
3674 |
| Alternate Names |
- CD41 antigen
- CD41
- CD41BHPA3
- GP2Bintegrin alpha-IIb
- GPalpha IIb
- GPIIb
- GTA
- integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41)
- integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41B)
- ITGAB
- platelet fibrinogen receptor, alpha subunit
- Platelet membrane glycoprotein IIb
- platelet-specific antigen BAK
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