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CD41/CD61 Antibody (JM11-19)

Images

 
Western Blot: CD41/CD61 Antibody (JM11-19) [NBP2-66757] - Analysis of CD41 on human placenta cells lysates using anti-CD41 antibody at 1/500 dilution.
Immunohistochemistry-Paraffin: CD41/CD61 Antibody (JM11-19) [NBP2-66757] - Analysis of paraffin-embedded human tonsil tissue using anti-CD41 antibody. Counter stained with hematoxylin.
Immunohistochemistry-Paraffin: CD41/CD61 Antibody (JM11-19) [NBP2-66757] - Analysis of paraffin-embedded human spleen tissue using anti-CD41 antibody. Counter stained with hematoxylin.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
JM11-19
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

CD41/CD61 Antibody (JM11-19) Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Synthetic peptide within Human CD41/CD61 aa 41-74 / 1039. (SwissProt: P08514 Human)
Localization
Membrane.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
ITGA2B
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
TBS (pH7.4), 0.05% BSA, 40% Glycerol
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for CD41/CD61 Antibody (JM11-19)

  • CD41 antigen
  • CD41
  • CD41BHPA3
  • GP2Bintegrin alpha-IIb
  • GPalpha IIb
  • GPIIb
  • GTA
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41)
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41B)
  • ITGAB
  • platelet fibrinogen receptor, alpha subunit
  • Platelet membrane glycoprotein IIb
  • platelet-specific antigen BAK

Background

Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ITGA2B