BAK Antibody Blocking Peptide

Bak a pro-apoptotic analog to Bax, is a member of the Bcl-2 family of proteins. During mitochondria-regulated programmed cell death, Bak promotes apoptosis by binding Bcl-2 and inhibiting its anti-apoptotic function (1). Upon apoptotic stimulation, Bak translocates from the cytosol to the mitochondrial membrane (2). Pro-apoptotic cascade activates BID, which oligomerizes Bak into pores that result in the release of cytochrome c (2, 3). In healthy cells, Bak associate with Bcl-xL and Mcl-1 but not with Bcl-2, Bcl-w or A1 and only when freed of both Bak will induce apoptosis.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

We have publications tested in 1 application: AC.

Showing Publication 1 - 1 of 1.

Publication using NBP1-77152PEP	Applications	Species
Marwarha G, Rosand O, Slagsvold KH, Hoydal MA GSK3 beta Inhibition Is the Molecular Pivot That Underlies the Mir-210-Induced Attenuation of Intrinsic Apoptosis Cascade during Hypoxia International journal of molecular sciences 2022-08-19 [PMID: 36012628] (AC)	AC

Array NBP1-77152PEP

• BAK Antibodies
• BAK ELISA Kits
• BAK Lysate
• BAK Protein
• BAK Proteins and Enzymes