Activin RIIB Antibody (60408)

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Members of the TGF-beta superfamily exert their biological effects by binding to heteromeric complexes of a type I and a type II serine-threonine kinase receptor, both of which are essential for signal transduction. Activin receptor type IIB is a type II receptor that mediates multiple signals for transforming growth factor-beta (TGF-beta ) family members, including Activin, Nodal, BMP-7, GDF-1, GDF-3, Myostatin (GDF-8), and GDF-11. Through alternative mRNA splicing, multiple ActR-IIB isoforms can also be generated.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC.

Showing Publications 1 - 2 of 2.

Publications using MAB3392	Applications	Species
Y Zhang, T Liu, X Hu, M Wang, J Wang, B Zou, P Tan, T Cui, Y Dou, L Ning, Y Huang, S Rao, D Wang, X Zhao CellCall: integrating paired ligand-receptor and transcription factor activities for cell-cell communication Nucleic Acids Research, 2021-09-07;0(0):. 2021-09-07 [PMID: 34331449] (IHC, Human)	IHC	Human
Bajikar SS, Wang CC, Borten MA et al. Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer Dev. Cell. 11/20/2017 [PMID: 29161592]

Array MAB3392

• Activin RIIB Antibodies
• Activin RIIB Lysate
• Activin RIIB Protein
• Activin RIIB Proteins and Enzymes