Cathepsin B Products

Description

The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S and O. The aspartyl protease class is composed of cathepsins D and E. cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. cathepsin B is expressed in luminal epithelial cells, indicating that cathepsin B is a marker for secretory cell death.

Bioinformatics

Entrez	13030 Mouse 1508 Human 64529 Rat
Uniprot	AAH10240 Human NM_001908 Human NM_147783 Human NP_001899.1 Human NP_680090 Human NP_680091 Human NP_680092 Human P07858 Human P10605 Mouse
Product By Gene ID	1508
Alternate Names	APP secretase APPS cathepsin B Cathepsin B1 CPSBamyloid precursor protein secretase cysteine protease EC 3.4.22 EC 3.4.22.1

Research Areas for Cathepsin B

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cellular Markers
Neuroscience

Related Cathepsin B Blog Posts

Check out the latest blog posts on Cathepsin B.

Caspase 11: A novel non-canonical inflammasomes Cell death via apoptosis is a key cellular function triggered by the cell death receptor family and their ligands. This regulated process then transmits downstream signals through adaptor molecules ending with the caspase cysteine proteases. Caspas...    Read more.

Cathepsin B - a lysosomal protease with potential of an important drug target in neurological diseases and cancer Cathepsins are a family of lysosomal proteases (serine, aspartic and cysteine proteases) that acts in conjunction with lipases and nucleases to degrade biological macromolecules in the lysosomes (1). While most cathepsins are ubiquitously expressed...    Read more.

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