Coagulation Factor II/Thrombin Products

Description

Proteinase-activated receptor 3 (PAR3) is a member of the Proteinase-Activated Receptor subfamily. The enzyme thrombin is involved in the activation of platelets, leukocytes, endothelial cells, and mesenchymal cells at sites of vascular injury. These cellular responses are triggered through proteolytic activation of PAR3 and other receptors by thrombin. It is believed that PAR3 functions as a cofactor for the cleavage and activation of PAR4. PAR3 expression has been documented in blood, bone marrow, lung, spleen, and vessel. ESTs have been isolated from head/neck, skeletal muscle, and skin libraries.

Bioinformatics

Entrez	2147 Human
Uniprot	P00734 Human
Product By Gene ID	2147
Alternate Names	coagulation factor II (thrombin) receptor-like 2 Coagulation factor II receptor-like 2 (protease-actovated receptor 3) Coagulation factor II receptor-like 2 Coagulation Factor II PAR-3 PAR3proteinase-activated receptor 3 protease-activated receptor 3 proteinase-activated receptor-3 PT serine protease Thrombin receptor-like 2

Research Areas for Coagulation Factor II/Thrombin

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