VDAC1 Antibody

VDAC1 is an outer membrane mitochondrial protein. The VDAC proteins are thought to form aqueous channels, or pores, through which adenine nucleotides cross the outer mitochondrial membrane. VDACs have been implicated in the formation of the mitochondrial permeability transition pore complex in apoptotic cells. This complex, formed by VDAC, adenine nucleotide translocator (ANT), and cyclophilin D (CypD), is thought to allow the mitochondria to undergo metabolic uncoupling and irreversible morphologic changes that ultimately destroy the mitochondria during apoptosis. VDACs are highly expressed in heart, liver and skeletal muscle, where concentrations of mitochondria are at their highest.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 5 confirmed species: Human, Mouse, Rat, Cynomolgus Monkey, Fish.

We have publications tested in 3 applications: KD, Simple Western, WB.

Showing Publications 1 - 9 of 9.

Publications using NB100-695	Applications	Species
Kam JH, Shinhmar H, Powner MB et al. Mitochondrial decline in the ageing old world primate retina: Little evidence for difference between the centre and periphery PloS one 2023-05-02 [PMID: 37130143] (WB, Cynomolgus Monkey) Details: 0.05ug/ml	WB	Cynomolgus Monkey
Arumugam S, Li B, Boodapati SLT et al. Mitochondrial DNA and the STING pathway are required for hepatic stellate cell activation Hepatology (Baltimore, Md.) 2023-04-05 [PMID: 37013923]
Moreau, M, Capallere, C, et al. Reconstruction of functional human epidermis equivalent containing 5%IPS-derived keratinocytes treated with mitochondrial stimulating plant extracts. Sci Rep [PMID: 35641783] (Simple Western, Human) Details: 0.180555556	Simple Western	Human
Go G, Yoon Ym, Yoon S Et Al. Melatonin Protects Chronic Kidney Disease Mesenchymal Stem/Stromal Cells against Accumulation of Methylglyoxal via Modulation of Hexokinase-2 Expression Biomolecules & therapeutics 2021-07-15 [PMID: 34261819] (WB)	WB
Liu KE, Frazier WA. Phosphorylation of the BNIP3 C-Terminus Inhibits Mitochondrial Damage and Cell Death without Blocking Autophagy PLoS ONE. 2015-06-24 [PMID: 26102349] (WB, Human)	WB	Human
Su YC, Chiu HW, Hung JC, Hong JR. Beta-nodavirus B2 protein induces hydrogen peroxide production, leading to Drp1-recruited mitochondrial fragmentation and cell death via mitochondrial targeting. Apoptosis 2014-07-10 [PMID: 25008790] (WB, Fish) Details: DRP1 antibody used for WB at 1:500 dilution on mitochondrial fractions isolated from Grouper/Epinephelus coioides cell line GF-1 cells (a cell line susceptible to grouper nervous necrosis virus - GNNV) transfected with EYFP or EYFP-B2 and treated with and without NAC or Mdivi for 48 h (Fig 6C).	WB	Fish
Chen H, Dzitoyeva S, Manev H. Effect of valproic acid on mitochondrial epigenetics Eur J Pharmacol 2012-06-20 [PMID: 22728245] (WB, Mouse)	WB	Mouse
Lee TY, Liu MS, Huang LJ, Lue SI. The Immediate Mitochondrial Stress Response in Coping with Systemic Exposure of Silver Nanoparticles in Rat Liver. Nanomedicine & Nanotechnology. 2014-08-27 (WB, Rat)	WB	Rat
Zhu Y, Liu Q, Liao M et al. Overexpression of LncRNA EPB41L4A-AS1 induces metabolic reprogramming in trophoblast cells and placenta tissue of miscarriage Molecular Therapy - Nucleic Acids 2019-09-01 [PMID: 31671345] (KD, WB, Human)	KD, WB	Human

Array NB100-695

• VDAC1 Antibodies
• VDAC1 Proteins