UCP3 Antibody

The uncoupling proteins (UCPs) are found in the inner mitochondrial membranes and belong to a family of mitochondrial anion transport proteins that include the phosphate and oxologutarate carriers and the ADP/ATP translocator. Three UCP subtypes have been identified and cloned. UCP 1 is abundantly expressed in brown adipose tissue of mammals. UCP 1 allows proton re-entry into the mitochondrial matrix without involving the F0-F1 ATPase which produces heat instead of ATP. It is thought that UCP 2 and 3 also dissipate the mitochondrial proton gradient produced by the respiratory chain in cells and tissues within which they are expressed. Studies have shown UCP 2 to be expressed by a variety of tissues. UCP 3 is expressed predominantly in brown adipose tissue, skeletal muscle, at lower levels in heart and smooth muscle, and is absent in liver and kidney.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: WB.

Showing Publications 1 - 3 of 3.

Publications using NBP2-24608	Applications	Species
Luo Z, Huang J, Li Z et al. Cajanolactone A, a Stilbenoid From Cajanus canjan (L.) Millsp, Prevents High-Fat Diet-Induced Obesity via Suppressing Energy Intake Frontiers in Pharmacology 2021-05-31 [PMID: 34135763]
Rupert JE, Narasimhan A, Jengelley DHA et al. Tumor-derived IL-6 and trans-signaling among tumor, fat, and muscle mediate pancreatic cancer cachexia The Journal of experimental medicine 2021-06-07 [PMID: 33851955] (WB, Mouse)	WB	Mouse
Sekerci G Sicanlara meteorin-like protein uygulamasının hipotalamus-hipofiz-tiroid aksı ve periferal uncoupling proteinler Uzerindeki etkileri Thesis 1905-07-13

Array NBP2-24608

• UCP3 Antibodies
• UCP3 ELISA Kit
• UCP3 Lysate
• UCP3 Proteins